Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence

W. M. Carroll; Y. Rochev; B. Clarke; M. Burke; D. J. Bradley; D. L. Plumley; J. Proft

Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence

W. M. Carroll, Y. Rochev, B. Clarke, M. Burke, D. J. Bradley, D. L. Plumley, J. Proft

Biomedical Engineering

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

6 Citations (Scopus)

Abstract

As the use of nitinol continues to grow in medical applications, so also does the need to acquire additional fundamental information regarding the stability of the material, in specific areas of deployment in the body. For devices fabricated from wires, data relating to the influence of wire surface state is an important consideration In the present study a range of wires, all in the shape set condition, but with subtle variations in surface preparation procedures are characterised in terms of surface roughness, cell surface interactions and polymer coating adhesion. Pickling of the wire leads to the roughest surface state while mechanical polishing after etching and pickling considerably reduces the surface roughness. Cell growth on all the different wire surfaces is good with the smoothest surface leading to the lowest degree of cell spreading. Quantitative procedures for measuring the adherence of polymer coatings on stents has become a very important experimental necessity as drug eluting stents become more widely used. This work reports on the first data measured for polymer coatings on nitinol wire substrates. The measured values of adhesion energy clearly show that adhesion is best when the wire surface state is at its roughest.

Original language	English
Title of host publication	Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003
Editors	S. Shrivastava
Pages	63-68
Number of pages	6
Publication status	Published - 2003
Event	Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003 - Anaheim, CA., United States Duration: 8 Sep 2003 → 10 Sep 2003

Publication series

Name	Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003

Conference

Conference	Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003
Country/Territory	United States
City	Anaheim, CA.
Period	8/09/03 → 10/09/03

Cite this

Carroll, W. M., Rochev, Y., Clarke, B., Burke, M., Bradley, D. J., Plumley, D. L., & Proft, J. (2003). Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence. In S. Shrivastava (Ed.), Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003 (pp. 63-68). (Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003).

Carroll, W. M. ; Rochev, Y. ; Clarke, B. et al. / Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence. Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003. editor / S. Shrivastava. 2003. pp. 63-68 (Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003).

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title = "Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence",

abstract = "As the use of nitinol continues to grow in medical applications, so also does the need to acquire additional fundamental information regarding the stability of the material, in specific areas of deployment in the body. For devices fabricated from wires, data relating to the influence of wire surface state is an important consideration In the present study a range of wires, all in the shape set condition, but with subtle variations in surface preparation procedures are characterised in terms of surface roughness, cell surface interactions and polymer coating adhesion. Pickling of the wire leads to the roughest surface state while mechanical polishing after etching and pickling considerably reduces the surface roughness. Cell growth on all the different wire surfaces is good with the smoothest surface leading to the lowest degree of cell spreading. Quantitative procedures for measuring the adherence of polymer coatings on stents has become a very important experimental necessity as drug eluting stents become more widely used. This work reports on the first data measured for polymer coatings on nitinol wire substrates. The measured values of adhesion energy clearly show that adhesion is best when the wire surface state is at its roughest.",

author = "Carroll, {W. M.} and Y. Rochev and B. Clarke and M. Burke and Bradley, {D. J.} and Plumley, {D. L.} and J. Proft",

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Carroll, WM, Rochev, Y, Clarke, B, Burke, M, Bradley, DJ, Plumley, DL & Proft, J 2003, Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence. in S Shrivastava (ed.), Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003. Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003, pp. 63-68, Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003, Anaheim, CA., United States, 8/09/03.

Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence. / Carroll, W. M.; Rochev, Y.; Clarke, B. et al.
Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003. ed. / S. Shrivastava. 2003. p. 63-68 (Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003).

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

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AU - Clarke, B.

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AU - Plumley, D. L.

AU - Proft, J.

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AB - As the use of nitinol continues to grow in medical applications, so also does the need to acquire additional fundamental information regarding the stability of the material, in specific areas of deployment in the body. For devices fabricated from wires, data relating to the influence of wire surface state is an important consideration In the present study a range of wires, all in the shape set condition, but with subtle variations in surface preparation procedures are characterised in terms of surface roughness, cell surface interactions and polymer coating adhesion. Pickling of the wire leads to the roughest surface state while mechanical polishing after etching and pickling considerably reduces the surface roughness. Cell growth on all the different wire surfaces is good with the smoothest surface leading to the lowest degree of cell spreading. Quantitative procedures for measuring the adherence of polymer coatings on stents has become a very important experimental necessity as drug eluting stents become more widely used. This work reports on the first data measured for polymer coatings on nitinol wire substrates. The measured values of adhesion energy clearly show that adhesion is best when the wire surface state is at its roughest.

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Carroll WM, Rochev Y, Clarke B, Burke M, Bradley DJ, Plumley DL et al. Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence. In Shrivastava S, editor, Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003. 2003. p. 63-68. (Medical Device Materials - Proceedings of the Materials and Processes for Medical Devices Conference 2003).

Influence of nitinol wire surface preparation procedures, on cell surface interactions and polymer coating adherence

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