Immunoglobulins in healthy controls: HLA‐B8 and sex differences Me HI rat wit ryl; riei ser

Eilis M. Cryan', Fiona M. Stevens, Rena Skehill, Mary Bourke, Helen Grimes, Ciaran F. Mccarthy

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

9 Citations (Scopus)

Abstract

Serum immunoglobulins were measured in one hundred and eighty‐four healthy controls. One hundred and fifty‐nine of these were also HLA typed. IgG levels did not differ with sex or HLA‐B8 status. IgM levels did not differ with HLA‐B8 status but were significantly higher in females than males. IgA levels were lower in females than males; they were also lower in HLA‐B8 positive compared with HLA‐B8 negative individuals; the lowest IgA levels were found in HLA‐B8 positive females. The IgA variation may be relevant to the higher incidence of certain disorders among HLA‐B8 positive individuals and among females.

Original languageEnglish
Pages (from-to)254-258
Number of pages5
JournalTissue Antigens
Volume26
Issue number4
DOIs
Publication statusPublished - Oct 1985
Externally publishedYes

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