Abstract
The existence of binding sites with high affinity for compounds containing the imidazoline moiety first became evident in the mid 1970's when it was found that the hypotensive response elicited by microinjection of the alpha-2 adrenoceptor agonist, clonidine, into the rat brainstem was not mimicked by norepinephrine .....
Original language | English |
---|---|
Title of host publication | xPharm |
Subtitle of host publication | The Comprehensive Pharmacology Reference |
Publisher | Elsevier Inc. |
Pages | 1-4 |
Number of pages | 4 |
ISBN (Print) | 9780080552323 |
DOIs | |
Publication status | Published - 2007 |