Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

G. Van Soest; T. P.M. Goderie; N. Gonzalo; S. Koljenović; G. L.J.H. Van Leenders; E. Regar; P. W. Serruys; A. F.W. Van Der Steen

doi:10.1007/BF03086301

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

G. Van Soest
, T. P.M. Goderie
, N. Gonzalo
, S. Koljenović
, G. L.J.H. Van Leenders
, E. Regar
, P. W. Serruys
, A. F.W. Van Der Steen

Erasmus MC
Interventional Cardiology

Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review

15 Citations (Scopus)

Abstract

Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μ_t distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μ_t≥10 mm^-1, while calcific and fibrous tissue have a lower μ_t≈2-5 mm^-1.

Original language	English
Pages (from-to)	448-450
Number of pages	3
Journal	Netherlands Heart Journal
Volume	17
Issue number	11
DOIs	https://doi.org/10.1007/BF03086301
Publication status	Published - Nov 2009
Externally published	Yes

Keywords

Atherosclerosis
Intravascular imaging
Optical coherence tomography
Tissue characterisation

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10.1007/BF03086301

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@article{d843fd56531346d08228525517430347,

title = "Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography",

abstract = "Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μt distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μt≥10 mm-1, while calcific and fibrous tissue have a lower μt≈2-5 mm-1.",

keywords = "Atherosclerosis, Intravascular imaging, Optical coherence tomography, Tissue characterisation",

author = "\{Van Soest\}, G. and Goderie, \{T. P.M.\} and N. Gonzalo and S. Koljenovi{\'c} and \{Van Leenders\}, \{G. L.J.H.\} and E. Regar and Serruys, \{P. W.\} and \{Van Der Steen\}, \{A. F.W.\}",

year = "2009",

month = nov,

doi = "10.1007/BF03086301",

language = "English",

volume = "17",

pages = "448--450",

journal = "Netherlands Heart Journal",

issn = "1568-5888",

publisher = "Bohn Stafleu van Loghum",

number = "11",

}

TY - JOUR

T1 - Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

AU - Van Soest, G.

AU - Goderie, T. P.M.

AU - Gonzalo, N.

AU - Koljenović, S.

AU - Van Leenders, G. L.J.H.

AU - Regar, E.

AU - Serruys, P. W.

AU - Van Der Steen, A. F.W.

PY - 2009/11

Y1 - 2009/11

N2 - Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μt distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μt≥10 mm-1, while calcific and fibrous tissue have a lower μt≈2-5 mm-1.

AB - Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μt distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μt≥10 mm-1, while calcific and fibrous tissue have a lower μt≈2-5 mm-1.

KW - Atherosclerosis

KW - Intravascular imaging

KW - Optical coherence tomography

KW - Tissue characterisation

UR - https://www.scopus.com/pages/publications/71649093056

U2 - 10.1007/BF03086301

DO - 10.1007/BF03086301

M3 - Review article

AN - SCOPUS:71649093056

SN - 1568-5888

VL - 17

SP - 448

EP - 450

JO - Netherlands Heart Journal

JF - Netherlands Heart Journal

IS - 11

ER -

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

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Keywords

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