Identification and Validation of Oncologic miRNA Biomarkers for Luminal A-like Breast Cancer.

Nicola Miller; Michael J. Kerin

doi:10.1371/journal.pone.0087032

Identification and Validation of Oncologic miRNA Biomarkers for Luminal A-like Breast Cancer.

Nicola Miller, Michael J. Kerin

Surgery

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Abstract

Breast cancer is a common disease with distinct tumor subtypes phenotypically characterized by ER and HER2 neu receptor status. MiRNAs play regulatory roles in tumor initiation and progression, and altered miRNA expression has been demonstrated in a variety of cancer states presenting the potential for exploitation as cancer biomarkers. Blood provides an excellent medium for biomarker discovery. This study investigated systemic miRNAs differentially expressed in Luminal A-like (ER+PR+HER2 neu-) breast cancer and their effectiveness as oncologic biomarkers in the clinical setting.

Original language	English (Ireland)
Article number	e87032
Journal	Plos One
Volume	9
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0087032
Publication status	Published - 1 Jan 2014

Authors (Note for portal: view the doc link for the full list of authors)

Authors
McDermott AM, Miller N, Wall D, Martyn LM, Ball G, Sweeney KJ, Kerin MJ

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1371/journal.pone.0087032

Cite this

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Identification and Validation of Oncologic miRNA Biomarkers for Luminal A-like Breast Cancer.

Abstract

Authors (Note for portal: view the doc link for the full list of authors)

UN SDGs

Access to Document

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