HLA types in liver disease in the west of Ireland

T. J. Kiernan; F. M. Stevens; M. Bourke; C. F. McCarthy

doi:10.1007/BF02939113

HLA types in liver disease in the west of Ireland

T. J. Kiernan, F. M. Stevens, M. Bourke, C. F. McCarthy

Galway University Hospital

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

3 Citations (Scopus)

Abstract

The frequency with which certain HLA types occur was determined in 47 patients with alcoholic liver disease and 20 patients with chronic active hepatitis (C.A.H.). These were compared with a control group of 105 healthy subjects. An increased incidence of HLA-A3, B5 and B40 were found in alcoholic cirrrhosis, but the results were not statistically significant. HLA-A28 and B17 were absent in the alcoholic cirrhotic group. The incidence of HLA-B8 was reduced, but not significantly, in the alcoholic cirrhotic group. Of the patients with C.A.H., HLA-B8 was increased, but failed to reach statistical significance.

Original language	English
Pages (from-to)	63-65
Number of pages	3
Journal	Irish Journal of Medical Science
Volume	149
Issue number	1
DOIs	https://doi.org/10.1007/BF02939113
Publication status	Published - Dec 1980
Externally published	Yes

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10.1007/BF02939113

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title = "HLA types in liver disease in the west of Ireland",

abstract = "The frequency with which certain HLA types occur was determined in 47 patients with alcoholic liver disease and 20 patients with chronic active hepatitis (C.A.H.). These were compared with a control group of 105 healthy subjects. An increased incidence of HLA-A3, B5 and B40 were found in alcoholic cirrrhosis, but the results were not statistically significant. HLA-A28 and B17 were absent in the alcoholic cirrhotic group. The incidence of HLA-B8 was reduced, but not significantly, in the alcoholic cirrhotic group. Of the patients with C.A.H., HLA-B8 was increased, but failed to reach statistical significance.",

author = "Kiernan, {T. J.} and Stevens, {F. M.} and M. Bourke and McCarthy, {C. F.}",

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T1 - HLA types in liver disease in the west of Ireland

AU - Kiernan, T. J.

AU - Stevens, F. M.

AU - Bourke, M.

AU - McCarthy, C. F.

PY - 1980/12

Y1 - 1980/12

N2 - The frequency with which certain HLA types occur was determined in 47 patients with alcoholic liver disease and 20 patients with chronic active hepatitis (C.A.H.). These were compared with a control group of 105 healthy subjects. An increased incidence of HLA-A3, B5 and B40 were found in alcoholic cirrrhosis, but the results were not statistically significant. HLA-A28 and B17 were absent in the alcoholic cirrhotic group. The incidence of HLA-B8 was reduced, but not significantly, in the alcoholic cirrhotic group. Of the patients with C.A.H., HLA-B8 was increased, but failed to reach statistical significance.

AB - The frequency with which certain HLA types occur was determined in 47 patients with alcoholic liver disease and 20 patients with chronic active hepatitis (C.A.H.). These were compared with a control group of 105 healthy subjects. An increased incidence of HLA-A3, B5 and B40 were found in alcoholic cirrrhosis, but the results were not statistically significant. HLA-A28 and B17 were absent in the alcoholic cirrhotic group. The incidence of HLA-B8 was reduced, but not significantly, in the alcoholic cirrhotic group. Of the patients with C.A.H., HLA-B8 was increased, but failed to reach statistical significance.

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ER -

HLA types in liver disease in the west of Ireland

Abstract

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