Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison

J. A. McKnight; S. H. Wild; M. J. E. Lamb; M. N. Cooper; T. W. Jones; E. A. Davis; S. Hofer; M. Fritsch; E. Schober; J. Svensson; T. Almdal; R. Young; J. T. Warner; B. Delemer; P. F. Souchon; R. W. Holl; W. Karges; D. M. Kieninger; S. Tigas; A. Bargiota; C. Sampanis; V. Cherubini; R. Gesuita; I. Strele; S. Pildava; K. J. Coppell; G. Magee; J. G. Cooper; S. F. Dinneen; K. Eeg-Olofsson; A.-M. Svensson; S. Gudbjornsdottir; H. Veeze; H.-J. Aanstoot; M. Khalangot; W. V. Tamborlane; K. M. Miller

doi:10.13025/26002

Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison

J. A. McKnight
, S. H. Wild
, M. J. E. Lamb
, M. N. Cooper
, T. W. Jones
, E. A. Davis
, S. Hofer
, M. Fritsch
, E. Schober
, J. Svensson
, T. Almdal
, R. Young
, J. T. Warner
, B. Delemer
, P. F. Souchon
, R. W. Holl
, W. Karges
, D. M. Kieninger
, S. Tigas
, A. Bargiota

C. Sampanis, V. Cherubini, R. Gesuita, I. Strele, S. Pildava, K. J. Coppell, G. Magee, J. G. Cooper, S. F. Dinneen, K. Eeg-Olofsson, A.-M. Svensson, S. Gudbjornsdottir, H. Veeze, H.-J. Aanstoot, M. Khalangot, W. V. Tamborlane, K. M. Miller

University of Edinburgh
University of Western Australia
Princess Margret Hospital for Children
The University of Western Australia
Medical University Innsbruck
Medical University Vienna
Gentofte University Hospital
Copenhagen University Hospital
Salford Royal NHS Foundation Trust
Children's Hospital for Wales
American Memorial Hospital
Ulm University
RWTH Aachen University
Medical Center of the Johannes Gutenberg University
University of Ioannina
University of Thessaly
Aristotle University of Thessaloniki
SalesiHospital
Università Politecnica delle Marche
Riga Stradins University
Centre for Disease Prevention and Control of Latvia
University of Otago
Daisy Hill Hospital
Noklus
Galway University Hospital
University of Galway
Sahlgrenska University Hospital
Centre of Registers in Region VöstraGötaland
National Centre for Pediatric and Adolescent Diabetes
Shupyk National Healthcare University of Ukraine
Yale University
Jaeb Centre for Health Research

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

297 Citations (Scopus)

Abstract

Aims: Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type 1 diabetes using data gathered in regional or national registries. Methods: Data were obtained for children and/or adults with Type 1 diabetes from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway, Northern Ireland, Scotland, Sweden, Volyn (Ukraine), USA and Wales) from population or clinic-based registries. The sample size with available data varied from 355 to 173 880. Proportions with HbA_1c < 58 mmol/mol (< 7.5%) and ≥ 75 mmol/mol (≥ 9.0%) were compared by age and sex. Results: Data were available for 324 501 people. The proportions with HbA_1c 58 mmol/mol (< 7.5%) varied from 15.7% to 46.4% among 44 058 people aged < 15 years, from 8.9% to 49.5% among 50 766 people aged 15-24 years and from 20.5% to 53.6% among 229 677 people aged ≥ 25 years. Sex differences in glycaemic control were small. Proportions of people using insulin pumps varied between the 12 sources with data available. Conclusion: These results suggest that there are substantial variations in glycaemic control among people with Type 1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults. What's new?: We present HbA_1c data from registries in 19 different countries describing control in 324 501 people with Type 1 diabetes, across all age groups. These data are the best representation of diabetes care available and therefore describe the 'state of the art'. We show clearly that Type 1 diabetes control is not as good as suggested in guidelines, but that some healthcare systems appear to result in better control than others. These data present a challenge to diabetes services. Leaders in diabetes units/service can compare their local data to our data and encourage improvement.

Original language	English (Ireland)
Pages (from-to)	1036-1050
Number of pages	15
Journal	Diabetic Medicine
Volume	32
Issue number	8
DOIs	https://doi.org/10.13025/26002 https://doi.org/10.1111/dme.12676
Publication status	Published - 1 Aug 2015

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10.13025/26002Licence: CC BY-NC-ND
10.1111/dme.12676

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McKnight, J. A., Wild, S. H., Lamb, M. J. E., Cooper, M. N., Jones, T. W., Davis, E. A., Hofer, S., Fritsch, M., Schober, E., Svensson, J., Almdal, T., Young, R., Warner, J. T., Delemer, B., Souchon, P. F., Holl, R. W., Karges, W., Kieninger, D. M., Tigas, S., ... Miller, K. M. (2015). Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison. Diabetic Medicine, 32(8), 1036-1050. https://doi.org/10.13025/26002, https://doi.org/10.1111/dme.12676

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title = "Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison",

abstract = "Aims: Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type 1 diabetes using data gathered in regional or national registries. Methods: Data were obtained for children and/or adults with Type 1 diabetes from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway, Northern Ireland, Scotland, Sweden, Volyn (Ukraine), USA and Wales) from population or clinic-based registries. The sample size with available data varied from 355 to 173 880. Proportions with HbA1c < 58 mmol/mol (< 7.5\%) and ≥ 75 mmol/mol (≥ 9.0\%) were compared by age and sex. Results: Data were available for 324 501 people. The proportions with HbA1c 58 mmol/mol (< 7.5\%) varied from 15.7\% to 46.4\% among 44 058 people aged < 15 years, from 8.9\% to 49.5\% among 50 766 people aged 15-24 years and from 20.5\% to 53.6\% among 229 677 people aged ≥ 25 years. Sex differences in glycaemic control were small. Proportions of people using insulin pumps varied between the 12 sources with data available. Conclusion: These results suggest that there are substantial variations in glycaemic control among people with Type 1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults. What's new?: We present HbA1c data from registries in 19 different countries describing control in 324 501 people with Type 1 diabetes, across all age groups. These data are the best representation of diabetes care available and therefore describe the 'state of the art'. We show clearly that Type 1 diabetes control is not as good as suggested in guidelines, but that some healthcare systems appear to result in better control than others. These data present a challenge to diabetes services. Leaders in diabetes units/service can compare their local data to our data and encourage improvement.",

author = "McKnight, \{J. A.\} and Wild, \{S. H.\} and Lamb, \{M. J. E.\} and Cooper, \{M. N.\} and Jones, \{T. W.\} and Davis, \{E. A.\} and S. Hofer and M. Fritsch and E. Schober and J. Svensson and T. Almdal and R. Young and Warner, \{J. T.\} and B. Delemer and Souchon, \{P. F.\} and Holl, \{R. W.\} and W. Karges and Kieninger, \{D. M.\} and S. Tigas and A. Bargiota and C. Sampanis and V. Cherubini and R. Gesuita and I. Strele and S. Pildava and Coppell, \{K. J.\} and G. Magee and Cooper, \{J. G.\} and Dinneen, \{S. F.\} and K. Eeg-Olofsson and A.-M. Svensson and S. Gudbjornsdottir and H. Veeze and H.-J. Aanstoot and M. Khalangot and Tamborlane, \{W. V.\} and Miller, \{K. M.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Diabetes UK.",

year = "2015",

month = aug,

day = "1",

doi = "10.13025/26002",

language = "English (Ireland)",

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journal = "Diabetic Medicine",

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McKnight, JA, Wild, SH, Lamb, MJE, Cooper, MN, Jones, TW, Davis, EA, Hofer, S, Fritsch, M, Schober, E, Svensson, J, Almdal, T, Young, R, Warner, JT, Delemer, B, Souchon, PF, Holl, RW, Karges, W, Kieninger, DM, Tigas, S, Bargiota, A, Sampanis, C, Cherubini, V, Gesuita, R, Strele, I, Pildava, S, Coppell, KJ, Magee, G, Cooper, JG, Dinneen, SF, Eeg-Olofsson, K, Svensson, A-M, Gudbjornsdottir, S, Veeze, H, Aanstoot, H-J, Khalangot, M, Tamborlane, WV & Miller, KM 2015, 'Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison', Diabetic Medicine, vol. 32, no. 8, pp. 1036-1050. https://doi.org/10.13025/26002, https://doi.org/10.1111/dme.12676

TY - JOUR

T1 - Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison.

T2 - An international comparison

AU - McKnight, J. A.

AU - Wild, S. H.

AU - Lamb, M. J. E.

AU - Cooper, M. N.

AU - Jones, T. W.

AU - Davis, E. A.

AU - Hofer, S.

AU - Fritsch, M.

AU - Schober, E.

AU - Svensson, J.

AU - Almdal, T.

AU - Young, R.

AU - Warner, J. T.

AU - Delemer, B.

AU - Souchon, P. F.

AU - Holl, R. W.

AU - Karges, W.

AU - Kieninger, D. M.

AU - Tigas, S.

AU - Bargiota, A.

AU - Sampanis, C.

AU - Cherubini, V.

AU - Gesuita, R.

AU - Strele, I.

AU - Pildava, S.

AU - Coppell, K. J.

AU - Magee, G.

AU - Cooper, J. G.

AU - Dinneen, S. F.

AU - Eeg-Olofsson, K.

AU - Svensson, A.-M.

AU - Gudbjornsdottir, S.

AU - Veeze, H.

AU - Aanstoot, H.-J.

AU - Khalangot, M.

AU - Tamborlane, W. V.

AU - Miller, K. M.

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Aims: Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type 1 diabetes using data gathered in regional or national registries. Methods: Data were obtained for children and/or adults with Type 1 diabetes from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway, Northern Ireland, Scotland, Sweden, Volyn (Ukraine), USA and Wales) from population or clinic-based registries. The sample size with available data varied from 355 to 173 880. Proportions with HbA1c < 58 mmol/mol (< 7.5%) and ≥ 75 mmol/mol (≥ 9.0%) were compared by age and sex. Results: Data were available for 324 501 people. The proportions with HbA1c 58 mmol/mol (< 7.5%) varied from 15.7% to 46.4% among 44 058 people aged < 15 years, from 8.9% to 49.5% among 50 766 people aged 15-24 years and from 20.5% to 53.6% among 229 677 people aged ≥ 25 years. Sex differences in glycaemic control were small. Proportions of people using insulin pumps varied between the 12 sources with data available. Conclusion: These results suggest that there are substantial variations in glycaemic control among people with Type 1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults. What's new?: We present HbA1c data from registries in 19 different countries describing control in 324 501 people with Type 1 diabetes, across all age groups. These data are the best representation of diabetes care available and therefore describe the 'state of the art'. We show clearly that Type 1 diabetes control is not as good as suggested in guidelines, but that some healthcare systems appear to result in better control than others. These data present a challenge to diabetes services. Leaders in diabetes units/service can compare their local data to our data and encourage improvement.

AB - Aims: Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type 1 diabetes using data gathered in regional or national registries. Methods: Data were obtained for children and/or adults with Type 1 diabetes from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway, Northern Ireland, Scotland, Sweden, Volyn (Ukraine), USA and Wales) from population or clinic-based registries. The sample size with available data varied from 355 to 173 880. Proportions with HbA1c < 58 mmol/mol (< 7.5%) and ≥ 75 mmol/mol (≥ 9.0%) were compared by age and sex. Results: Data were available for 324 501 people. The proportions with HbA1c 58 mmol/mol (< 7.5%) varied from 15.7% to 46.4% among 44 058 people aged < 15 years, from 8.9% to 49.5% among 50 766 people aged 15-24 years and from 20.5% to 53.6% among 229 677 people aged ≥ 25 years. Sex differences in glycaemic control were small. Proportions of people using insulin pumps varied between the 12 sources with data available. Conclusion: These results suggest that there are substantial variations in glycaemic control among people with Type 1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults. What's new?: We present HbA1c data from registries in 19 different countries describing control in 324 501 people with Type 1 diabetes, across all age groups. These data are the best representation of diabetes care available and therefore describe the 'state of the art'. We show clearly that Type 1 diabetes control is not as good as suggested in guidelines, but that some healthcare systems appear to result in better control than others. These data present a challenge to diabetes services. Leaders in diabetes units/service can compare their local data to our data and encourage improvement.

UR - http://hdl.handle.net/10379/12824

UR - https://www.scopus.com/pages/publications/84948716018

U2 - 10.13025/26002

DO - 10.13025/26002

M3 - Article

VL - 32

SP - 1036

EP - 1050

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 8

ER -

Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison. : An international comparison

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