TY - JOUR
T1 - George Gabriel Stokes as a biologist
T2 - George Gabriel Stokes as a biologist
AU - Ceredig, Rhodri
N1 - Publisher Copyright:
© 2020 The Author(s).
PY - 2020/9/4
Y1 - 2020/9/4
N2 - It is universally acknowledged that George Gabriel Stokes (1819-1903) was a polymath who made major contributions to the fields of mathematics, chemistry, physics, fluidics and optics. However, his contributions to biology have received far less attention and this brief communication examines two of Stokes' major biological contributions, namely his description of the phenomenon of fluorescence and his studies on the changes in the colour of blood following oxidation and reduction. The paper on fluorescence is discussed because in it, Stokes demonstrates his wide-ranging biological knowledge and because the use of fluorescence is an invaluable experimental tool in biology. It was by developing the experimental approaches and equipment used to investigate fluorescence that Stokes then applied these to other investigations, including that of blood. From what we now know, what Stokes was describing in his paper on blood were the changes in the configuration of the haemoglobin molecule upon the acquisition and release of oxygen. This article is part of the theme issue 'Stokes at 200 (part 2)'.
AB - It is universally acknowledged that George Gabriel Stokes (1819-1903) was a polymath who made major contributions to the fields of mathematics, chemistry, physics, fluidics and optics. However, his contributions to biology have received far less attention and this brief communication examines two of Stokes' major biological contributions, namely his description of the phenomenon of fluorescence and his studies on the changes in the colour of blood following oxidation and reduction. The paper on fluorescence is discussed because in it, Stokes demonstrates his wide-ranging biological knowledge and because the use of fluorescence is an invaluable experimental tool in biology. It was by developing the experimental approaches and equipment used to investigate fluorescence that Stokes then applied these to other investigations, including that of blood. From what we now know, what Stokes was describing in his paper on blood were the changes in the configuration of the haemoglobin molecule upon the acquisition and release of oxygen. This article is part of the theme issue 'Stokes at 200 (part 2)'.
KW - biology
KW - blood
KW - flow cytometry
KW - fluorescence
KW - haemoglobin
UR - https://www.scopus.com/pages/publications/85089302155
U2 - 10.1098/rsta.2020.0105
DO - 10.1098/rsta.2020.0105
M3 - Article
C2 - 32762439
AN - SCOPUS:85089302155
SN - 1364-503X
VL - 378
JO - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
JF - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
IS - 2179
M1 - 20200105
ER -