TY - JOUR
T1 - Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge Stylissa aff. carteri Collected off the Futuna Islands
AU - Miguel-Gordo, Maria
AU - Gegunde, Sandra
AU - Jennings, Laurence K.
AU - Genta-Jouve, Grégory
AU - Calabro, Kevin
AU - Alfonso, Amparo
AU - Botana, Luis M.
AU - Thomas, Olivier P.
N1 - Publisher Copyright:
Copyright © 2020 American Chemical Society and American Society of Pharmacognosy.
PY - 2020/7/24
Y1 - 2020/7/24
N2 - The chemical investigation of the sponge Stylissa aff. carteri collected around Futuna Islands in the Pacific Ocean led to the isolation of three new dimeric pyrrole 2-aminoimidazole alkaloids (PIAs). Futunamine (1) features an unprecedented pyrrolo[1,2-c]imidazole core, while two other new dimeric PIAs were identified as analogues of palau'amine. Together with other known PIAs isolated from this species, they were shown to exhibit anti-inflammatory and neuroprotective activities.
AB - The chemical investigation of the sponge Stylissa aff. carteri collected around Futuna Islands in the Pacific Ocean led to the isolation of three new dimeric pyrrole 2-aminoimidazole alkaloids (PIAs). Futunamine (1) features an unprecedented pyrrolo[1,2-c]imidazole core, while two other new dimeric PIAs were identified as analogues of palau'amine. Together with other known PIAs isolated from this species, they were shown to exhibit anti-inflammatory and neuroprotective activities.
UR - http://www.scopus.com/inward/record.url?scp=85088381467&partnerID=8YFLogxK
U2 - 10.1021/acs.jnatprod.0c00223
DO - 10.1021/acs.jnatprod.0c00223
M3 - Article
C2 - 32628481
AN - SCOPUS:85088381467
SN - 0163-3864
VL - 83
SP - 2299
EP - 2304
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 7
ER -