Fostering responsible research with genome editing technologies: a European perspective

Hervé Chneiweiss; François Hirsch; Lluis Montoliu; Albrecht M. Müller; Solveig Fenet; Marion Abecassis; Jennifer Merchant; Bernard Baertschi; Mylène Botbol-Baum; James A. Houghton; Mihalis Kritikos; Janet Mifsud; Ewa Bartnik; Johannes Rath; Christiane Druml; Bärbel Friedrich; Ana Sofia Carvalho; Dirk Lanzerath; Agnès Saint-Raymond

doi:10.13025/28357

Fostering responsible research with genome editing technologies: a European perspective

Hervé Chneiweiss
, François Hirsch
, Lluis Montoliu
, Albrecht M. Müller
, Solveig Fenet
, Marion Abecassis
, Jennifer Merchant
, Bernard Baertschi
, Mylène Botbol-Baum
, James A. Houghton
, Mihalis Kritikos
, Janet Mifsud
, Ewa Bartnik
, Johannes Rath
, Christiane Druml
, Bärbel Friedrich
, Ana Sofia Carvalho
, Dirk Lanzerath
, Agnès Saint-Raymond

Infectious Disease

Inserm
ISCIII
University of Wuerzburg
University Panthéon-Assas
University of Geneva
Université Catholique de Louvain
Vrije Universiteit Brussel
University of Malta
University of Warsaw
University of Vienna
Medical University Vienna
German National Academy of Sciences Leopoldina
Universidade Católica Portuguesa
European Research Ethics Committee Network (EUREC)
European Medicines Agency

Research output: Contribution to a Journal (Peer & Non Peer) › Letter › peer-review

29 Citations (Scopus)

Abstract

In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome editing (off-targets, mosaicisms, etc.), and to design risk matrices and scenarios for a responsible use of this promising technology. In addition, this European steering committee will contribute in promoting an open debate on societal aspects prior to a translation into national and international legislation.

Original language	English
Pages (from-to)	709-713
Number of pages	5
Journal	Transgenic Research
Volume	26
Issue number	5
DOIs	https://doi.org/10.13025/28357 https://doi.org/10.1007/s11248-017-0028-z
Publication status	Published - 1 Oct 2017

Keywords

CRISPR-Cas
Gene editing
Responsible research and innovation
Science and society

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10.13025/28357Licence: CC BY-NC-ND
10.1007/s11248-017-0028-z

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Chneiweiss, H., Hirsch, F., Montoliu, L., Müller, A. M., Fenet, S., Abecassis, M., Merchant, J., Baertschi, B., Botbol-Baum, M., Houghton, J. A., Kritikos, M., Mifsud, J., Bartnik, E., Rath, J., Druml, C., Friedrich, B., Carvalho, A. S., Lanzerath, D., & Saint-Raymond, A. (2017). Fostering responsible research with genome editing technologies: a European perspective. Transgenic Research, 26(5), 709-713. https://doi.org/10.13025/28357, https://doi.org/10.1007/s11248-017-0028-z

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title = "Fostering responsible research with genome editing technologies: a European perspective",

abstract = "In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome editing (off-targets, mosaicisms, etc.), and to design risk matrices and scenarios for a responsible use of this promising technology. In addition, this European steering committee will contribute in promoting an open debate on societal aspects prior to a translation into national and international legislation.",

keywords = "CRISPR-Cas, Gene editing, Responsible research and innovation, Science and society",

author = "Herv{\'e} Chneiweiss and Fran{\c c}ois Hirsch and Lluis Montoliu and M{\"u}ller, \{Albrecht M.\} and Solveig Fenet and Marion Abecassis and Jennifer Merchant and Bernard Baertschi and Myl{\`e}ne Botbol-Baum and Houghton, \{James A.\} and Mihalis Kritikos and Janet Mifsud and Ewa Bartnik and Johannes Rath and Christiane Druml and B{\"a}rbel Friedrich and Carvalho, \{Ana Sofia\} and Dirk Lanzerath and Agn{\`e}s Saint-Raymond",

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Chneiweiss, H, Hirsch, F, Montoliu, L, Müller, AM, Fenet, S, Abecassis, M, Merchant, J, Baertschi, B, Botbol-Baum, M, Houghton, JA, Kritikos, M, Mifsud, J, Bartnik, E, Rath, J, Druml, C, Friedrich, B, Carvalho, AS, Lanzerath, D & Saint-Raymond, A 2017, 'Fostering responsible research with genome editing technologies: a European perspective', Transgenic Research, vol. 26, no. 5, pp. 709-713. https://doi.org/10.13025/28357, https://doi.org/10.1007/s11248-017-0028-z

TY - JOUR

T1 - Fostering responsible research with genome editing technologies

T2 - a European perspective

AU - Chneiweiss, Hervé

AU - Hirsch, François

AU - Montoliu, Lluis

AU - Müller, Albrecht M.

AU - Fenet, Solveig

AU - Abecassis, Marion

AU - Merchant, Jennifer

AU - Baertschi, Bernard

AU - Botbol-Baum, Mylène

AU - Houghton, James A.

AU - Kritikos, Mihalis

AU - Mifsud, Janet

AU - Bartnik, Ewa

AU - Rath, Johannes

AU - Druml, Christiane

AU - Friedrich, Bärbel

AU - Carvalho, Ana Sofia

AU - Lanzerath, Dirk

AU - Saint-Raymond, Agnès

PY - 2017/10/1

Y1 - 2017/10/1

N2 - In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome editing (off-targets, mosaicisms, etc.), and to design risk matrices and scenarios for a responsible use of this promising technology. In addition, this European steering committee will contribute in promoting an open debate on societal aspects prior to a translation into national and international legislation.

AB - In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome editing (off-targets, mosaicisms, etc.), and to design risk matrices and scenarios for a responsible use of this promising technology. In addition, this European steering committee will contribute in promoting an open debate on societal aspects prior to a translation into national and international legislation.

KW - CRISPR-Cas

KW - Gene editing

KW - Responsible research and innovation

KW - Science and society

UR - http://hdl.handle.net/10379/10778

UR - https://www.scopus.com/pages/publications/85025134861

U2 - 10.13025/28357

DO - 10.13025/28357

M3 - Letter

C2 - 28730514

SN - 0962-8819

VL - 26

SP - 709

EP - 713

JO - Transgenic Research

JF - Transgenic Research

IS - 5

ER -

Fostering responsible research with genome editing technologies: a European perspective

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Keywords

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