First-line treatment of chronic myeloid leukaemia

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Abstract

Since the introduction of imatinib just over a decade ago, there has been a dramatic change in the treatment and prognosis of early chronic phase chronic myeloid leukaemia (CML). This review article focuses on recent advances, culminating in the approval of nilotinib by the US Food and Drug Administration for the treatment of adult patients with newly diagnosed CML in the chronic phase.

Original languageEnglish
Pages (from-to)15-22
Number of pages8
JournalTherapeutic Advances in Hematology
Volume1
Issue number1
DOIs
Publication statusPublished - Dec 2010
Externally publishedYes

Keywords

  • CML
  • early chronic phase
  • treatment
  • tyrosine kinase inhibitor

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