Finding useful biomarkers for Parkinson s disease

Alice S. Chen-Plotkin; Roge Albin; Ro Alcalay; Debr Babcock; Vikra Bajaj; Duboi Bowman; Ale Buko; Jess Cedarbaum; Danie Chelsky; Mar R. Cookson; Te M. Dawson; Richar Dewey; Tatian Foroud; Mar Frasier; Dwigh German; Katrin Gwinn; Xueme Huang; Catherin Kopil; Thoma Kremer; Shirle Lasch; Ke Marek; Jarro A. Marto; Kalpan Merchant; Bri Mollenhauer; Ann Naito; Judit Potashkin; Alyss Reimer; Lian S. Rosenthal; Rache Saunders-Pullman; Clemen R. Scherzer; Tod Sherer; Andre Singleton; Margare Sutherland; Ine Thiele; Marce Van Der Brug; Kendall Van Keuren-Jensen; Davi Vaillancourt; Davi Walt; Andre West; Jin Zhang

doi:10.1126/scitranslmed.aam6003

Finding useful biomarkers for Parkinson s disease

Alice S. Chen-Plotkin
, Roge Albin
, Ro Alcalay
, Debr Babcock
, Vikra Bajaj
, Duboi Bowman
, Ale Buko
, Jess Cedarbaum
, Danie Chelsky
, Mar R. Cookson
, Te M. Dawson
, Richar Dewey
, Tatian Foroud
, Mar Frasier
, Dwigh German
, Katrin Gwinn
, Xueme Huang
, Catherin Kopil
, Thoma Kremer
, Shirle Lasch

Ke Marek, Jarro A. Marto, Kalpan Merchant, Bri Mollenhauer, Ann Naito, Judit Potashkin, Alyss Reimer, Lian S. Rosenthal, Rache Saunders-Pullman, Clemen R. Scherzer, Tod Sherer, Andre Singleton, Margare Sutherland, Ine Thiele, Marce Van Der Brug, Kendall Van Keuren-Jensen, Davi Vaillancourt, Davi Walt, Andre West, Jin Zhang

University of Pennsylvania Perelman School of Medicine
VAAHS
University of Michigan Medical School
Columbia University Medical Center
Synaptic Function Section
Verily/Google Life Sciences
Mailman School of Public Health
Human Metabolome Technology America
Biogen Inc.
Montreal
National Institute of Aging
The Johns Hopkins University School of Medicine
University of Texas Southwestern Medical Center
Indiana University School of Medicine
Michael J. Fox Foundation for Parkinson s Research
University of Texas Southwestern Medical Center
Penn State University-Hershey Medical Center
Roche Innovation Center
Institute for Neurodegenerative Disorders
Harvard Medical School
Brigham and Women's Hospital
Chaperone Therapeutics
Paracelsus-Elena-Klinik
University Medical Centre Göttingen
Chicago Medical School
Icahn School of Medicine at Mount Sinai
National Institute on Aging (NIA)
University of Luxembourg
Department of Cancer Immunology
Translational Genomics Research Institute
University of Florida
University of Alabama
University of Washington

Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review

104 Citations (Scopus)

Abstract

The recent advent of an ecosystem of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson s disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.

Original language	English
Article number	eaam6003
Journal	Science Translational Medicine
Volume	10
Issue number	454
DOIs	https://doi.org/10.1126/scitranslmed.aam6003
Publication status	Published - 15 Aug 2018
Externally published	Yes

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10.1126/scitranslmed.aam6003

Cite this

Chen-Plotkin, A. S., Albin, R., Alcalay, R., Babcock, D., Bajaj, V., Bowman, D., Buko, A., Cedarbaum, J., Chelsky, D., Cookson, M. R., Dawson, T. M., Dewey, R., Foroud, T., Frasier, M., German, D., Gwinn, K., Huang, X., Kopil, C., Kremer, T., ... Zhang, J. (2018). Finding useful biomarkers for Parkinson s disease. Science Translational Medicine, 10(454), Article eaam6003. https://doi.org/10.1126/scitranslmed.aam6003

@article{169d58e24d234e54a5ed8e04161c1f03,

title = "Finding useful biomarkers for Parkinson s disease",

abstract = "The recent advent of an ecosystem of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson s disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.",

author = "Chen-Plotkin, \{Alice S.\} and Roge Albin and Ro Alcalay and Debr Babcock and Vikra Bajaj and Duboi Bowman and Ale Buko and Jess Cedarbaum and Danie Chelsky and Cookson, \{Mar R.\} and Dawson, \{Te M.\} and Richar Dewey and Tatian Foroud and Mar Frasier and Dwigh German and Katrin Gwinn and Xueme Huang and Catherin Kopil and Thoma Kremer and Shirle Lasch and Ke Marek and Marto, \{Jarro A.\} and Kalpan Merchant and Bri Mollenhauer and Ann Naito and Judit Potashkin and Alyss Reimer and Rosenthal, \{Lian S.\} and Rache Saunders-Pullman and Scherzer, \{Clemen R.\} and Tod Sherer and Andre Singleton and Margare Sutherland and Ine Thiele and \{Van Der Brug\}, Marce and Keuren-Jensen, \{Kendall Van\} and Davi Vaillancourt and Davi Walt and Andre West and Jin Zhang",

note = "Publisher Copyright: {\textcopyright} 2018 The Authors.",

year = "2018",

month = aug,

day = "15",

doi = "10.1126/scitranslmed.aam6003",

language = "English",

volume = "10",

journal = "Science Translational Medicine",

issn = "1946-6234",

publisher = "American Association for the Advancement of Science",

number = "454",

}

Chen-Plotkin, AS, Albin, R, Alcalay, R, Babcock, D, Bajaj, V, Bowman, D, Buko, A, Cedarbaum, J, Chelsky, D, Cookson, MR, Dawson, TM, Dewey, R, Foroud, T, Frasier, M, German, D, Gwinn, K, Huang, X, Kopil, C, Kremer, T, Lasch, S, Marek, K, Marto, JA, Merchant, K, Mollenhauer, B, Naito, A, Potashkin, J, Reimer, A, Rosenthal, LS, Saunders-Pullman, R, Scherzer, CR, Sherer, T, Singleton, A, Sutherland, M, Thiele, I, Van Der Brug, M, Keuren-Jensen, KV, Vaillancourt, D, Walt, D, West, A & Zhang, J 2018, 'Finding useful biomarkers for Parkinson s disease', Science Translational Medicine, vol. 10, no. 454, eaam6003. https://doi.org/10.1126/scitranslmed.aam6003

TY - JOUR

T1 - Finding useful biomarkers for Parkinson s disease

AU - Chen-Plotkin, Alice S.

AU - Albin, Roge

AU - Alcalay, Ro

AU - Babcock, Debr

AU - Bajaj, Vikra

AU - Bowman, Duboi

AU - Buko, Ale

AU - Cedarbaum, Jess

AU - Chelsky, Danie

AU - Cookson, Mar R.

AU - Dawson, Te M.

AU - Dewey, Richar

AU - Foroud, Tatian

AU - Frasier, Mar

AU - German, Dwigh

AU - Gwinn, Katrin

AU - Huang, Xueme

AU - Kopil, Catherin

AU - Kremer, Thoma

AU - Lasch, Shirle

AU - Marek, Ke

AU - Marto, Jarro A.

AU - Merchant, Kalpan

AU - Mollenhauer, Bri

AU - Naito, Ann

AU - Potashkin, Judit

AU - Reimer, Alyss

AU - Rosenthal, Lian S.

AU - Saunders-Pullman, Rache

AU - Scherzer, Clemen R.

AU - Sherer, Tod

AU - Singleton, Andre

AU - Sutherland, Margare

AU - Thiele, Ine

AU - Van Der Brug, Marce

AU - Keuren-Jensen, Kendall Van

AU - Vaillancourt, Davi

AU - Walt, Davi

AU - West, Andre

AU - Zhang, Jin

PY - 2018/8/15

Y1 - 2018/8/15

N2 - The recent advent of an ecosystem of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson s disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.

AB - The recent advent of an ecosystem of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson s disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.

UR - https://www.scopus.com/pages/publications/85052005906

U2 - 10.1126/scitranslmed.aam6003

DO - 10.1126/scitranslmed.aam6003

M3 - Review article

C2 - 30111645

AN - SCOPUS:85052005906

SN - 1946-6234

VL - 10

JO - Science Translational Medicine

JF - Science Translational Medicine

IS - 454

M1 - eaam6003

ER -

Finding useful biomarkers for Parkinson s disease

Abstract

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