Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide

Padraig O'Connor; Rongbing Yang; William M. Carroll; Yury Rochev; Fawaz Aldabbagh

doi:10.1016/j.eurpolymj.2012.04.011

Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide

Padraig O'Connor, Rongbing Yang, William M. Carroll, Yury Rochev, Fawaz Aldabbagh

Biomedical Engineering

University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

23 Citations (Scopus)

Abstract

A new protocol for preparation of thermoresponsive poly(N- isopropylacrylamide, NIPAM) containing block copolymers is described. It involves two successive heterogeneous controlled/living nitroxide-mediated polymerizations (NMPs) in supercritical carbon dioxide (scCO ₂) using N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (SG1), as the nitroxide. Precipitation NMPs give narrow dispersity macroinitiators (MIs), and a first report of the controlled/living polymerization of N,N-dimethylacrylamide (DMA) in scCO ₂ is described. The MI is then used in an inverse suspension NMP of NIPAM in scCO ₂ resulting in the efficient preparation of block copolymers containing DMA, tert-butyl acrylate and styrene. Aqueous cloud point temperature analysis for poly(DMA)-b-poly(NIPAM) and poly(acrylic acid)-b-poly(NIPAM) shows a significant dependence on poly(NIPAM) chain length for a given AB block copolymer.

Original language	English
Pages (from-to)	1279-1288
Number of pages	10
Journal	European Polymer Journal
Volume	48
Issue number	7
DOIs	https://doi.org/10.1016/j.eurpolymj.2012.04.011
Publication status	Published - Jul 2012

Keywords

Macroinitiator
Polymer
Precipitation polymerisation
Radical
Reversible-deactivation
Suspension polymerisation

Access to Document

10.1016/j.eurpolymj.2012.04.011

Cite this

@article{18504501624541c7b94905d2bf71ca95,

title = "Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide",

abstract = "A new protocol for preparation of thermoresponsive poly(N- isopropylacrylamide, NIPAM) containing block copolymers is described. It involves two successive heterogeneous controlled/living nitroxide-mediated polymerizations (NMPs) in supercritical carbon dioxide (scCO 2) using N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (SG1), as the nitroxide. Precipitation NMPs give narrow dispersity macroinitiators (MIs), and a first report of the controlled/living polymerization of N,N-dimethylacrylamide (DMA) in scCO 2 is described. The MI is then used in an inverse suspension NMP of NIPAM in scCO 2 resulting in the efficient preparation of block copolymers containing DMA, tert-butyl acrylate and styrene. Aqueous cloud point temperature analysis for poly(DMA)-b-poly(NIPAM) and poly(acrylic acid)-b-poly(NIPAM) shows a significant dependence on poly(NIPAM) chain length for a given AB block copolymer.",

keywords = "Macroinitiator, Polymer, Precipitation polymerisation, Radical, Reversible-deactivation, Suspension polymerisation",

author = "Padraig O'Connor and Rongbing Yang and Carroll, \{William M.\} and Yury Rochev and Fawaz Aldabbagh",

year = "2012",

month = jul,

doi = "10.1016/j.eurpolymj.2012.04.011",

language = "English",

volume = "48",

pages = "1279--1288",

journal = "European Polymer Journal",

issn = "0014-3057",

publisher = "Elsevier Ltd",

number = "7",

}

Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide. / O'Connor, Padraig; Yang, Rongbing; Carroll, William M. et al.
In: European Polymer Journal, Vol. 48, No. 7, 07.2012, p. 1279-1288.

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

TY - JOUR

T1 - Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide

AU - O'Connor, Padraig

AU - Yang, Rongbing

AU - Carroll, William M.

AU - Rochev, Yury

AU - Aldabbagh, Fawaz

PY - 2012/7

Y1 - 2012/7

N2 - A new protocol for preparation of thermoresponsive poly(N- isopropylacrylamide, NIPAM) containing block copolymers is described. It involves two successive heterogeneous controlled/living nitroxide-mediated polymerizations (NMPs) in supercritical carbon dioxide (scCO 2) using N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (SG1), as the nitroxide. Precipitation NMPs give narrow dispersity macroinitiators (MIs), and a first report of the controlled/living polymerization of N,N-dimethylacrylamide (DMA) in scCO 2 is described. The MI is then used in an inverse suspension NMP of NIPAM in scCO 2 resulting in the efficient preparation of block copolymers containing DMA, tert-butyl acrylate and styrene. Aqueous cloud point temperature analysis for poly(DMA)-b-poly(NIPAM) and poly(acrylic acid)-b-poly(NIPAM) shows a significant dependence on poly(NIPAM) chain length for a given AB block copolymer.

AB - A new protocol for preparation of thermoresponsive poly(N- isopropylacrylamide, NIPAM) containing block copolymers is described. It involves two successive heterogeneous controlled/living nitroxide-mediated polymerizations (NMPs) in supercritical carbon dioxide (scCO 2) using N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (SG1), as the nitroxide. Precipitation NMPs give narrow dispersity macroinitiators (MIs), and a first report of the controlled/living polymerization of N,N-dimethylacrylamide (DMA) in scCO 2 is described. The MI is then used in an inverse suspension NMP of NIPAM in scCO 2 resulting in the efficient preparation of block copolymers containing DMA, tert-butyl acrylate and styrene. Aqueous cloud point temperature analysis for poly(DMA)-b-poly(NIPAM) and poly(acrylic acid)-b-poly(NIPAM) shows a significant dependence on poly(NIPAM) chain length for a given AB block copolymer.

KW - Macroinitiator

KW - Polymer

KW - Precipitation polymerisation

KW - Radical

KW - Reversible-deactivation

KW - Suspension polymerisation

UR - https://www.scopus.com/pages/publications/84862902125

U2 - 10.1016/j.eurpolymj.2012.04.011

DO - 10.1016/j.eurpolymj.2012.04.011

M3 - Article

SN - 0014-3057

VL - 48

SP - 1279

EP - 1288

JO - European Polymer Journal

JF - European Polymer Journal

IS - 7

ER -

Facile synthesis of thermoresponsive block copolymers of N-isopropylacrylamide using heterogeneous controlled/living nitroxide-mediated polymerizations in supercritical carbon dioxide

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this