Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: A case report

Deirdre F. Waterhouse; Geraldine A. Moloney; Fatma S. Gargoum; Peter S. Hayden; Tom O'Gorman

doi:10.4076/1757-1626-2-7456

Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: A case report

Deirdre F. Waterhouse
, Geraldine A. Moloney
, Fatma S. Gargoum
, Peter S. Hayden
, Tom O'Gorman

Galway University Hospital

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

6 Citations (Scopus)

Abstract

Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.

Original language	English
Article number	7456
Journal	Cases Journal
Volume	2
Issue number	9
DOIs	https://doi.org/10.4076/1757-1626-2-7456
Publication status	Published - Sept 2009
Externally published	Yes

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title = "Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: A case report",

abstract = "Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.",

author = "Waterhouse, \{Deirdre F.\} and Moloney, \{Geraldine A.\} and Gargoum, \{Fatma S.\} and Hayden, \{Peter S.\} and Tom O'Gorman",

year = "2009",

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T2 - A case report

AU - Waterhouse, Deirdre F.

AU - Moloney, Geraldine A.

AU - Gargoum, Fatma S.

AU - Hayden, Peter S.

AU - O'Gorman, Tom

PY - 2009/9

Y1 - 2009/9

N2 - Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.

AB - Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.

UR - https://www.scopus.com/pages/publications/77953460330

U2 - 10.4076/1757-1626-2-7456

DO - 10.4076/1757-1626-2-7456

M3 - Article

AN - SCOPUS:77953460330

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VL - 2

JO - Cases Journal

JF - Cases Journal

IS - 9

M1 - 7456

ER -

Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: A case report

Abstract

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