TY - JOUR
T1 - Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy
T2 - A case report
AU - Waterhouse, Deirdre F.
AU - Moloney, Geraldine A.
AU - Gargoum, Fatma S.
AU - Hayden, Peter S.
AU - O'Gorman, Tom
PY - 2009/9
Y1 - 2009/9
N2 - Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.
AB - Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.
UR - http://www.scopus.com/inward/record.url?scp=77953460330&partnerID=8YFLogxK
U2 - 10.4076/1757-1626-2-7456
DO - 10.4076/1757-1626-2-7456
M3 - Article
AN - SCOPUS:77953460330
SN - 1757-1626
VL - 2
JO - Cases Journal
JF - Cases Journal
IS - 9
M1 - 7456
ER -