Endoplasmic reticulum stress: At the crossroads of inflammation and metabolism in hepatocellular carcinoma development

Marion Maurel, Afshin Samali, Eric Chevet

Research output: Contribution to a Journal (Peer & Non Peer)Short surveypeer-review

34 Citations (Scopus)

Abstract

Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic reticulum stress signaling is instrumental in the development of steatohepatitis and synergizes with proinflammatory pathways to promote hepatocarcinogenesis.

Original languageEnglish
Pages (from-to)301-303
Number of pages3
JournalCancer Cell
Volume26
Issue number3
DOIs
Publication statusPublished - 2014

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