TY - JOUR
T1 - Effect on cell surface hydrophobicity and susceptibility of Helicobacter pylori to medicinal plant extracts
AU - Annuk, Heidi
AU - Hirmo, Siiri
AU - Türi, Endel
AU - Mikelsaar, Marika
AU - Arak, Elmar
AU - Wadström, Torkel
PY - 1999/3/1
Y1 - 1999/3/1
N2 - Effects of aqueous extracts of medicinal plants on ten Helicobacter pylori strains were studied by the salt aggregation test to determine the possibility to modulate their cell surface hydrophobicity and by an agar diffusion assay for detection of antimicrobial activity. It was established that aqueous extracts of bearberry and cowberry leaves enhance cell aggregation of all H. pylori strains tested by the salt aggregation test, and the extract of bearberry possessed a remarkable bacteriostatic activity. Pure tannic acid showed a result similar to that of bearberry and cowberry extracts which contained a large amount of tannins. In contrast, extracts of wild camomile and pineapple-weed, which blocked aggregation of H. pylori, contained small amounts of tannins and did not reveal any antimicrobial activity. Tannic acid seems to be the component of bearberry and cowberry aqueous extracts with the highest activity to decrease cell surface hydrophobicity as well as in antibacterial activity against H. pylori. Copyright (C) 1999 Federation of European Microbiological Societies.
AB - Effects of aqueous extracts of medicinal plants on ten Helicobacter pylori strains were studied by the salt aggregation test to determine the possibility to modulate their cell surface hydrophobicity and by an agar diffusion assay for detection of antimicrobial activity. It was established that aqueous extracts of bearberry and cowberry leaves enhance cell aggregation of all H. pylori strains tested by the salt aggregation test, and the extract of bearberry possessed a remarkable bacteriostatic activity. Pure tannic acid showed a result similar to that of bearberry and cowberry extracts which contained a large amount of tannins. In contrast, extracts of wild camomile and pineapple-weed, which blocked aggregation of H. pylori, contained small amounts of tannins and did not reveal any antimicrobial activity. Tannic acid seems to be the component of bearberry and cowberry aqueous extracts with the highest activity to decrease cell surface hydrophobicity as well as in antibacterial activity against H. pylori. Copyright (C) 1999 Federation of European Microbiological Societies.
KW - Antibacterial activity
KW - Cell aggregation
KW - Cell surface hydrophobicity
KW - Helicobacter pylori
KW - Medicinal plant
UR - http://www.scopus.com/inward/record.url?scp=0033065747&partnerID=8YFLogxK
U2 - 10.1016/S0378-1097(99)00002-6
DO - 10.1016/S0378-1097(99)00002-6
M3 - Article
C2 - 10079525
AN - SCOPUS:0033065747
SN - 0378-1097
VL - 172
SP - 41
EP - 45
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
IS - 1
ER -