Abstract
Thirty nine patients undergoing elective uncomplicated surgical procedures of various types were studied to determine the pattern of change induced by surgical operation on tests commonly used in the laboratory to diagnose intravascular coagulation. The most striking observations were the following. The fibrinogen level became increased in 87% of patients, peaking on the third to fourth postoperative day when the mean (±SD) value was 539 ± 119 mg/dl. Fibrinolytic split products (FSP) invariably became significantly increased, the degree of change being independent of the type of surgical procedure and of the clinical course. Additionally, 90% of patients had a value of 48 μg/ml or higher at some time. The peak mean FSP value occurred on the third to fourth postoperative day. Ethanol and protamine gelation tests became positive in 51% and 33% of patients, respectively, at some time postoperatively.
| Original language | English |
|---|---|
| Pages (from-to) | 658-664 |
| Number of pages | 7 |
| Journal | Mayo Clinic Proceedings |
| Volume | 49 |
| Issue number | 9 |
| Publication status | Published - 1974 |
| Externally published | Yes |