Abstract
Variation at the dysbindin gene (DTNBP1) has been associated with increased risk for schizophrenia in numerous independent samples and recently with deficits in general and domain-specific cognitive processing. The relationship between dysbindin risk variants and sensory-level deficits in schizophrenia remains to be explored. We investigated P1 performance, a component of early visual processing on which both patients and their relatives show deficits, in carriers and noncarriers of a known dysbindin risk haplotype.
| Original language | English (Ireland) |
|---|---|
| Pages (from-to) | 484-489 |
| Number of pages | 6 |
| Journal | Biological Psychiatry |
| Volume | 63 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1 Mar 2008 |
Keywords
- Dysbindin
- EEG
- ERP
- P1
- schizophrenia
- sensory processing
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Donohoe G, Morris DW, De Sanctis P, Magno E, Montesi JL, Garavan HP, Robertson IH, Javitt DC, Gill M, Corvin AP, Foxe JJ
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