Dissection of an inflammatory process induced by CD8+ T cells

Peter C. Doherty; Jane E. Allan; Felicity Lynch; Rhodri Ceredig

doi:10.1016/0167-5699(90)90020-A

Dissection of an inflammatory process induced by CD8⁺ T cells

Peter C. Doherty, Jane E. Allan, Felicity Lynch, Rhodri Ceredig

Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review

159 Citations (Scopus)

Abstract

A massive delayed type hypersensitivity (DTH) reaction occurs in the cerebrospinal fluid (CSF) of mice with lymphocytic choriomeningitis (LCM). In this article, Peter Doherty and colleagues analyze this reaction together with the population dynamics of the regional lymph node to give a comprehensive picture of the events underlying this CD8⁺ T-cell-mediated immunopathological disease. Their findings are of general relevance to the understanding of inflammation.

Original language	English
Pages (from-to)	60-65
Number of pages	6
Journal	Immunology Today
Volume	11
Issue number	C
DOIs	https://doi.org/10.1016/0167-5699(90)90020-A
Publication status	Published - 1990
Externally published	Yes

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10.1016/0167-5699(90)90020-A

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@article{188dd55cf144405c83c87949fc141385,

title = "Dissection of an inflammatory process induced by CD8+ T cells",

abstract = "A massive delayed type hypersensitivity (DTH) reaction occurs in the cerebrospinal fluid (CSF) of mice with lymphocytic choriomeningitis (LCM). In this article, Peter Doherty and colleagues analyze this reaction together with the population dynamics of the regional lymph node to give a comprehensive picture of the events underlying this CD8+ T-cell-mediated immunopathological disease. Their findings are of general relevance to the understanding of inflammation.",

author = "Doherty, \{Peter C.\} and Allan, \{Jane E.\} and Felicity Lynch and Rhodri Ceredig",

year = "1990",

doi = "10.1016/0167-5699(90)90020-A",

language = "English",

volume = "11",

pages = "60--65",

journal = "Immunology Today",

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publisher = "Elsevier B.V.",

number = "C",

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T1 - Dissection of an inflammatory process induced by CD8+ T cells

AU - Doherty, Peter C.

AU - Allan, Jane E.

AU - Lynch, Felicity

AU - Ceredig, Rhodri

PY - 1990

Y1 - 1990

N2 - A massive delayed type hypersensitivity (DTH) reaction occurs in the cerebrospinal fluid (CSF) of mice with lymphocytic choriomeningitis (LCM). In this article, Peter Doherty and colleagues analyze this reaction together with the population dynamics of the regional lymph node to give a comprehensive picture of the events underlying this CD8+ T-cell-mediated immunopathological disease. Their findings are of general relevance to the understanding of inflammation.

AB - A massive delayed type hypersensitivity (DTH) reaction occurs in the cerebrospinal fluid (CSF) of mice with lymphocytic choriomeningitis (LCM). In this article, Peter Doherty and colleagues analyze this reaction together with the population dynamics of the regional lymph node to give a comprehensive picture of the events underlying this CD8+ T-cell-mediated immunopathological disease. Their findings are of general relevance to the understanding of inflammation.

UR - https://www.scopus.com/pages/publications/44949266542

U2 - 10.1016/0167-5699(90)90020-A

DO - 10.1016/0167-5699(90)90020-A

M3 - Review article

SN - 0167-5699

VL - 11

SP - 60

EP - 65

JO - Immunology Today

JF - Immunology Today

IS - C

ER -

Dissection of an inflammatory process induced by CD8⁺ T cells

Abstract

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