TY - GEN
T1 - Diffuse reflection imaging of sub-epidermal tissue haematocrit using a simple RGB camera
AU - Leahy, Martin J.
AU - O'Doherty, Jim
AU - McNamara, Paul
AU - Henricson, Joakim
AU - Nilsson, Gert E.
AU - Anderson, Chris
AU - Sjoberg, Folke
PY - 2007
Y1 - 2007
N2 - This paper describes the design and evaluation of a novel easy to use, tissue viability imaging system (TiVi). The system is based on the methods of diffuse reflectance spectroscopy and polarization spectroscopy. The technique has been developed as an alternative to current imaging technology in the area of microcirculation imaging, most notably optical coherence tomography (OCT) and laser Doppler perfusion imaging (LDPI). The system is based on standard digital camera technology, and is sensitive to red blood cells (RBCs) in the microcirculation. Lack of clinical acceptance of both OCT and LDPI fuels the need for an objective, simple, reproducible and portable imaging method that can provide accurate measurements related to stimulus vasoactivity in the microvasculature. The limitations of these technologies are discussed in this paper. Uses of the Tissue Viability system include skin care products, drug development, and assessment spatial and temporal aspects of vasodilation (erythema) and vasoconstriction (blanching).
AB - This paper describes the design and evaluation of a novel easy to use, tissue viability imaging system (TiVi). The system is based on the methods of diffuse reflectance spectroscopy and polarization spectroscopy. The technique has been developed as an alternative to current imaging technology in the area of microcirculation imaging, most notably optical coherence tomography (OCT) and laser Doppler perfusion imaging (LDPI). The system is based on standard digital camera technology, and is sensitive to red blood cells (RBCs) in the microcirculation. Lack of clinical acceptance of both OCT and LDPI fuels the need for an objective, simple, reproducible and portable imaging method that can provide accurate measurements related to stimulus vasoactivity in the microvasculature. The limitations of these technologies are discussed in this paper. Uses of the Tissue Viability system include skin care products, drug development, and assessment spatial and temporal aspects of vasodilation (erythema) and vasoconstriction (blanching).
KW - Blood flow
KW - Diffuse reflectance spectroscopy
KW - Inflammation
KW - Laser Doppler perfusion imaging (LDPI)
KW - Microcirculation imaging
KW - Optical coherence tomography (OCT)
KW - Polarization spectroscopy
UR - https://www.scopus.com/pages/publications/34848860322
U2 - 10.1117/12.740600
DO - 10.1117/12.740600
M3 - Conference Publication
AN - SCOPUS:34848860322
SN - 0819466573
SN - 9780819466570
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Saratov Fall Meeting 2006
T2 - Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII
Y2 - 26 September 2006 through 29 September 2006
ER -