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Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications

  • D. A. Pollacco
  • , M. Caligari Conti
  • , L. Farrugia
  • , P. Schembri Wismayer
  • , L. Farina
  • , C. V. Sammut
  • University of Malta
  • Sapienza University of Rome
  • University of Galway

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

10 Citations (Scopus)

Abstract

The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. This implied that such solutions can be utilized in the construction of human body phantoms for narrowband and ultra-wideband microwave devices for near field breast cancer imaging.

Original languageEnglish
Article number095009
JournalPhysics in Medicine and Biology
Volume64
Issue number9
DOIs
Publication statusPublished - 26 Apr 2019
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • adipose
  • microwave ablation
  • microwave imaging
  • muscle
  • tissue mimicking solutions

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