Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland

C. Newman; A. M. Egan; T. Ahern; M. Al-Kiyumi; G. Balan; M. J. Brassill; E. Brosnan; L. Carmody; H. Clarke; C. Coogan Kelly; L. Culliney; R. Davern; M. Durkan; M. Fenlon; P. Ferry; G. Hanlon; T. Higgins; S. Hoashi; A. Khamis; B. Kinsley; B. Kirwan; P. Kyithar; A. Liew; L. Matthews; C. McGurk; C. McHugh; M. S. Murphy; P. Murphy; D. Nagodra; E. Noctor; M. Nolan; E. O'Connor; D. O'Halloran; L. O'Mahoney; E. O'Sullivan; M. Peters; G. Roberts; H. Rooney; A. Smyth; B. Tarachand; M. Todd; A. Tuthill; W. A. Wan Mahmood; O. Yousif; F. P. Dunne

doi:10.1016/j.diabres.2021.108685

Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland

C. Newman
, A. M. Egan
, T. Ahern
, M. Al-Kiyumi
, G. Balan
, M. J. Brassill
, E. Brosnan
, L. Carmody
, H. Clarke
, C. Coogan Kelly
, L. Culliney
, R. Davern
, M. Durkan
, M. Fenlon
, P. Ferry
, G. Hanlon
, T. Higgins
, S. Hoashi
, A. Khamis
, B. Kinsley

B. Kirwan, P. Kyithar, A. Liew, L. Matthews, C. McGurk, C. McHugh, M. S. Murphy, P. Murphy, D. Nagodra, E. Noctor, M. Nolan, E. O'Connor, D. O'Halloran, L. O'Mahoney, E. O'Sullivan, M. Peters, G. Roberts, H. Rooney, A. Smyth, B. Tarachand, M. Todd, A. Tuthill, W. A. Wan Mahmood, O. Yousif, F. P. Dunne

Medicine

Galway University Hospital
Mayo Clinic
Our Lady of Lourdes Hospital Drogheda
Coombe Women and Infants University Hospital
South Tipperary General Hospital
Mayo University Hospital
Portiuncula University Hospital
St Luke's General Hospital Carlow Kilkenny
Regional Hospital
Bon Secours Hospital Cork
Wexford General Hospital
Letterkenny University Hospital
University Hospital Kerry
Mullingar Regional Hospital
Portlaoise General Hospital
Sligo University Hospital
South Infirmary Victoria Hospital
Limerick Regional General Hospital
University Hospital Waterford

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

25 Citations (Scopus)

Abstract

Aims: Pre-gestational diabetes mellitus (PGDM) is associated with adverse outcomes. We aimed to examine pregnancies affected by PGDM; report on these pregnancy outcomes and compare outcomes for patients with type 1 versus type 2 diabetes mellitus; compare our findings to published Irish and United Kingdom (UK) data and identify potential areas for improvement. Methods: Between 2016 and 2018 information on 679 pregnancies from 415 women with type 1 Diabetes Mellitus and 244 women with type 2 diabetes was analysed. Data was collected on maternal characteristics; pregnancy preparation; glycaemic control; pregnancy related complications; foetal and maternal outcomes; unscheduled hospitalisations; congenital anomalies and perinatal deaths. Results: Only 15.9% of women were adequately prepared for pregnancy. Significant deficits were identified in availability and attendance at pre-pregnancy clinic, use of folic acid, attaining appropriate glycaemic targets and appropriate retinal screening. The majority of pregnancies (n = 567, 83.5%) resulted in a live birth but the large number of infants born large for gestational age (LGA) (n = 280, 49.4%), born prematurely <37 weeks and requiring neonatal intensive care unit (NICU) admission continue to be significant issues. Conclusions: This retrospective cohort study identifies multiple targets for improvements in the provision of care to women with pre-gestational DM which are likely to translate into better pregnancy outcomes.

Original language	English
Article number	108685
Journal	Diabetes Research and Clinical Practice
Volume	173
DOIs	https://doi.org/10.1016/j.diabres.2021.108685
Publication status	Published - Mar 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diabetes
Pre-existing
Pre-gestational
Pregnancy

Authors (Note for portal: view the doc link for the full list of authors)

Authors
Newman C;Egan AM;Ahern T;Al-Kiyumi M;Balan G;Brassill MJ;Brosnan E;Carmody L;Clarke H;Coogan Kelly C;Culliney L;Davern R;Durkan M;Fenlon M;Ferry P;Hanlon G;Higgins T;Hoashi S;Khamis A;Kinsley B;Kirwan B;Kyithar P;Liew A;Matthews L;McGurk C;McHugh C;Murphy MS;Murphy P;Nagodra D;Noctor E;Nolan M;O'Connor E;O'Halloran D;O'Mahoney L;O'Sullivan E;Peters M;Roberts G;Rooney H;Smyth A;Tarachand B;Todd M;Tuthill A;Wan Mahmood WA;Yousif O;Dunne FP;

Access to Document

10.1016/j.diabres.2021.108685

Cite this

Newman, C., Egan, A. M., Ahern, T., Al-Kiyumi, M., Balan, G., Brassill, M. J., Brosnan, E., Carmody, L., Clarke, H., Coogan Kelly, C., Culliney, L., Davern, R., Durkan, M., Fenlon, M., Ferry, P., Hanlon, G., Higgins, T., Hoashi, S., Khamis, A., ... Dunne, F. P. (2021). Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland. Diabetes Research and Clinical Practice, 173, Article 108685. https://doi.org/10.1016/j.diabres.2021.108685

@article{8b73c0e90f7148238e7da42d49858d3e,

title = "Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland",

abstract = "Aims: Pre-gestational diabetes mellitus (PGDM) is associated with adverse outcomes. We aimed to examine pregnancies affected by PGDM; report on these pregnancy outcomes and compare outcomes for patients with type 1 versus type 2 diabetes mellitus; compare our findings to published Irish and United Kingdom (UK) data and identify potential areas for improvement. Methods: Between 2016 and 2018 information on 679 pregnancies from 415 women with type 1 Diabetes Mellitus and 244 women with type 2 diabetes was analysed. Data was collected on maternal characteristics; pregnancy preparation; glycaemic control; pregnancy related complications; foetal and maternal outcomes; unscheduled hospitalisations; congenital anomalies and perinatal deaths. Results: Only 15.9\% of women were adequately prepared for pregnancy. Significant deficits were identified in availability and attendance at pre-pregnancy clinic, use of folic acid, attaining appropriate glycaemic targets and appropriate retinal screening. The majority of pregnancies (n = 567, 83.5\%) resulted in a live birth but the large number of infants born large for gestational age (LGA) (n = 280, 49.4\%), born prematurely <37 weeks and requiring neonatal intensive care unit (NICU) admission continue to be significant issues. Conclusions: This retrospective cohort study identifies multiple targets for improvements in the provision of care to women with pre-gestational DM which are likely to translate into better pregnancy outcomes.",

keywords = "Diabetes, Pre-existing, Pre-gestational, Pregnancy",

author = "C. Newman and Egan, \{A. M.\} and T. Ahern and M. Al-Kiyumi and G. Balan and Brassill, \{M. J.\} and E. Brosnan and L. Carmody and H. Clarke and \{Coogan Kelly\}, C. and L. Culliney and R. Davern and M. Durkan and M. Fenlon and P. Ferry and G. Hanlon and T. Higgins and S. Hoashi and A. Khamis and B. Kinsley and B. Kirwan and P. Kyithar and A. Liew and L. Matthews and C. McGurk and C. McHugh and Murphy, \{M. S.\} and P. Murphy and D. Nagodra and E. Noctor and M. Nolan and E. O'Connor and D. O'Halloran and L. O'Mahoney and E. O'Sullivan and M. Peters and G. Roberts and H. Rooney and A. Smyth and B. Tarachand and M. Todd and A. Tuthill and \{Wan Mahmood\}, \{W. A.\} and O. Yousif and Dunne, \{F. P.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",

year = "2021",

month = mar,

doi = "10.1016/j.diabres.2021.108685",

language = "English",

volume = "173",

journal = "Diabetes Research and Clinical Practice",

issn = "0168-8227",

publisher = "Elsevier Ireland Ltd",

}

Newman, C, Egan, AM, Ahern, T, Al-Kiyumi, M, Balan, G, Brassill, MJ, Brosnan, E, Carmody, L, Clarke, H, Coogan Kelly, C, Culliney, L, Davern, R, Durkan, M, Fenlon, M, Ferry, P, Hanlon, G, Higgins, T, Hoashi, S, Khamis, A, Kinsley, B, Kirwan, B, Kyithar, P, Liew, A, Matthews, L, McGurk, C, McHugh, C, Murphy, MS, Murphy, P, Nagodra, D, Noctor, E, Nolan, M, O'Connor, E, O'Halloran, D, O'Mahoney, L, O'Sullivan, E, Peters, M, Roberts, G, Rooney, H, Smyth, A, Tarachand, B, Todd, M, Tuthill, A, Wan Mahmood, WA, Yousif, O & Dunne, FP 2021, 'Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland', Diabetes Research and Clinical Practice, vol. 173, 108685. https://doi.org/10.1016/j.diabres.2021.108685

TY - JOUR

T1 - Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland

AU - Newman, C.

AU - Egan, A. M.

AU - Ahern, T.

AU - Al-Kiyumi, M.

AU - Balan, G.

AU - Brassill, M. J.

AU - Brosnan, E.

AU - Carmody, L.

AU - Clarke, H.

AU - Coogan Kelly, C.

AU - Culliney, L.

AU - Davern, R.

AU - Durkan, M.

AU - Fenlon, M.

AU - Ferry, P.

AU - Hanlon, G.

AU - Higgins, T.

AU - Hoashi, S.

AU - Khamis, A.

AU - Kinsley, B.

AU - Kirwan, B.

AU - Kyithar, P.

AU - Liew, A.

AU - Matthews, L.

AU - McGurk, C.

AU - McHugh, C.

AU - Murphy, M. S.

AU - Murphy, P.

AU - Nagodra, D.

AU - Noctor, E.

AU - Nolan, M.

AU - O'Connor, E.

AU - O'Halloran, D.

AU - O'Mahoney, L.

AU - O'Sullivan, E.

AU - Peters, M.

AU - Roberts, G.

AU - Rooney, H.

AU - Smyth, A.

AU - Tarachand, B.

AU - Todd, M.

AU - Tuthill, A.

AU - Wan Mahmood, W. A.

AU - Yousif, O.

AU - Dunne, F. P.

PY - 2021/3

Y1 - 2021/3

N2 - Aims: Pre-gestational diabetes mellitus (PGDM) is associated with adverse outcomes. We aimed to examine pregnancies affected by PGDM; report on these pregnancy outcomes and compare outcomes for patients with type 1 versus type 2 diabetes mellitus; compare our findings to published Irish and United Kingdom (UK) data and identify potential areas for improvement. Methods: Between 2016 and 2018 information on 679 pregnancies from 415 women with type 1 Diabetes Mellitus and 244 women with type 2 diabetes was analysed. Data was collected on maternal characteristics; pregnancy preparation; glycaemic control; pregnancy related complications; foetal and maternal outcomes; unscheduled hospitalisations; congenital anomalies and perinatal deaths. Results: Only 15.9% of women were adequately prepared for pregnancy. Significant deficits were identified in availability and attendance at pre-pregnancy clinic, use of folic acid, attaining appropriate glycaemic targets and appropriate retinal screening. The majority of pregnancies (n = 567, 83.5%) resulted in a live birth but the large number of infants born large for gestational age (LGA) (n = 280, 49.4%), born prematurely <37 weeks and requiring neonatal intensive care unit (NICU) admission continue to be significant issues. Conclusions: This retrospective cohort study identifies multiple targets for improvements in the provision of care to women with pre-gestational DM which are likely to translate into better pregnancy outcomes.

AB - Aims: Pre-gestational diabetes mellitus (PGDM) is associated with adverse outcomes. We aimed to examine pregnancies affected by PGDM; report on these pregnancy outcomes and compare outcomes for patients with type 1 versus type 2 diabetes mellitus; compare our findings to published Irish and United Kingdom (UK) data and identify potential areas for improvement. Methods: Between 2016 and 2018 information on 679 pregnancies from 415 women with type 1 Diabetes Mellitus and 244 women with type 2 diabetes was analysed. Data was collected on maternal characteristics; pregnancy preparation; glycaemic control; pregnancy related complications; foetal and maternal outcomes; unscheduled hospitalisations; congenital anomalies and perinatal deaths. Results: Only 15.9% of women were adequately prepared for pregnancy. Significant deficits were identified in availability and attendance at pre-pregnancy clinic, use of folic acid, attaining appropriate glycaemic targets and appropriate retinal screening. The majority of pregnancies (n = 567, 83.5%) resulted in a live birth but the large number of infants born large for gestational age (LGA) (n = 280, 49.4%), born prematurely <37 weeks and requiring neonatal intensive care unit (NICU) admission continue to be significant issues. Conclusions: This retrospective cohort study identifies multiple targets for improvements in the provision of care to women with pre-gestational DM which are likely to translate into better pregnancy outcomes.

KW - Diabetes

KW - Pre-existing

KW - Pre-gestational

KW - Pregnancy

UR - https://www.scopus.com/pages/publications/85101327485

U2 - 10.1016/j.diabres.2021.108685

DO - 10.1016/j.diabres.2021.108685

M3 - Article

SN - 0168-8227

VL - 173

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

M1 - 108685

ER -

Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland

Abstract

UN SDGs

Keywords

Authors (Note for portal: view the doc link for the full list of authors)

Access to Document

Other files and links

Fingerprint

Cite this