DETERMINATION OF TYRAMINE IN ALCOHOLIC AND NONALCOHOLIC BEERS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION

ANTHONY M. WHEATLEY; KEITH F. TIPTON

doi:10.1111/j.1745-4514.1987.tb00118.x

DETERMINATION OF TYRAMINE IN ALCOHOLIC AND NONALCOHOLIC BEERS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION

ANTHONY M. WHEATLEY, KEITH F. TIPTON

Trinity College Dublin

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

7 Citations (Scopus)

Abstract

A simple method for the isolation of tyramine from alcoholic and nonalcoholic beers and its subsequent analysis by HPLC with electrochemical detection has been developed. Ultrafiltration of the beer followed by a cation‐exchange step provided clear resolution of the tyramine peak and greatly shortened the assay time. The concentration of tyramine in the alcoholic beers ranged from 0.98 to 3.21 mg L⁻¹ and in the nonalcoholic beers from 0.52 to 3.96mg L⁻¹. The possible hazard of consumption of both types of beer to patients on monoamine oxidase inhibitor treatment is discussed. The application of the method to the determination in other beverages is also demonstrated.

Original language	English
Pages (from-to)	133-142
Number of pages	10
Journal	Journal of Food Biochemistry
Volume	11
Issue number	2
DOIs	https://doi.org/10.1111/j.1745-4514.1987.tb00118.x
Publication status	Published - Jun 1987
Externally published	Yes

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title = "DETERMINATION OF TYRAMINE IN ALCOHOLIC AND NONALCOHOLIC BEERS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION",

abstract = "A simple method for the isolation of tyramine from alcoholic and nonalcoholic beers and its subsequent analysis by HPLC with electrochemical detection has been developed. Ultrafiltration of the beer followed by a cation‐exchange step provided clear resolution of the tyramine peak and greatly shortened the assay time. The concentration of tyramine in the alcoholic beers ranged from 0.98 to 3.21 mg L−1 and in the nonalcoholic beers from 0.52 to 3.96mg L−1. The possible hazard of consumption of both types of beer to patients on monoamine oxidase inhibitor treatment is discussed. The application of the method to the determination in other beverages is also demonstrated.",

author = "WHEATLEY, \{ANTHONY M.\} and TIPTON, \{KEITH F.\}",

year = "1987",

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AU - WHEATLEY, ANTHONY M.

AU - TIPTON, KEITH F.

PY - 1987/6

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N2 - A simple method for the isolation of tyramine from alcoholic and nonalcoholic beers and its subsequent analysis by HPLC with electrochemical detection has been developed. Ultrafiltration of the beer followed by a cation‐exchange step provided clear resolution of the tyramine peak and greatly shortened the assay time. The concentration of tyramine in the alcoholic beers ranged from 0.98 to 3.21 mg L−1 and in the nonalcoholic beers from 0.52 to 3.96mg L−1. The possible hazard of consumption of both types of beer to patients on monoamine oxidase inhibitor treatment is discussed. The application of the method to the determination in other beverages is also demonstrated.

AB - A simple method for the isolation of tyramine from alcoholic and nonalcoholic beers and its subsequent analysis by HPLC with electrochemical detection has been developed. Ultrafiltration of the beer followed by a cation‐exchange step provided clear resolution of the tyramine peak and greatly shortened the assay time. The concentration of tyramine in the alcoholic beers ranged from 0.98 to 3.21 mg L−1 and in the nonalcoholic beers from 0.52 to 3.96mg L−1. The possible hazard of consumption of both types of beer to patients on monoamine oxidase inhibitor treatment is discussed. The application of the method to the determination in other beverages is also demonstrated.

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ER -

DETERMINATION OF TYRAMINE IN ALCOHOLIC AND NONALCOHOLIC BEERS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION

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