TY - JOUR
T1 - Detection and characterization of coronary bifurcation lesions with 64-slice computed tomography coronary angiography
AU - Van Mieghem, Carlos A.G.
AU - Thury, Attila
AU - Meijboom, Willem B.
AU - Cademartiri, Filippo
AU - Mollet, Nico R.
AU - Weustink, Annick C.
AU - Sianos, Georgios
AU - De Jaegere, Peter P.T.
AU - Serruys, Patrick W.
AU - De Feyter, Pim
PY - 2007/8
Y1 - 2007/8
N2 - Aims: To compare the performance of 64-slice computed tomography coronary angiography (CTCA) and invasive coronary angiography (ICA) in the detection and classification (according to the Medina system) of bifurcation lesions (BLs). Methods and results: We studied 323 consecutive patients undergoing 64-slice CTCA prior to ICA. All coronary segments ≥2 mm in diameter were evaluated for the presence of a significant (≥50% diameter reduction on quantitative coronary angiography) BL. Evaluation of BL by CTCA included the assessment of significant lumen obstruction in both main and side branch vessels. Forty-one out of 43 patients (46/48 lesions) with significant BL were identified by CTCA. Excluding coronary segments with non-diagnostic image quality (5%), the sensitivity, specificity, and positive and negative predictive values of CTCA for detecting significant BL were 96, 99, and 85 and 99%, respectively. In 39 of these 41 patients, CTCA assessment was concordant with the Medina lesion classification on ICA. Conclusion: Sixty-four-slice CTCA allows accurate assessment of complex BL.
AB - Aims: To compare the performance of 64-slice computed tomography coronary angiography (CTCA) and invasive coronary angiography (ICA) in the detection and classification (according to the Medina system) of bifurcation lesions (BLs). Methods and results: We studied 323 consecutive patients undergoing 64-slice CTCA prior to ICA. All coronary segments ≥2 mm in diameter were evaluated for the presence of a significant (≥50% diameter reduction on quantitative coronary angiography) BL. Evaluation of BL by CTCA included the assessment of significant lumen obstruction in both main and side branch vessels. Forty-one out of 43 patients (46/48 lesions) with significant BL were identified by CTCA. Excluding coronary segments with non-diagnostic image quality (5%), the sensitivity, specificity, and positive and negative predictive values of CTCA for detecting significant BL were 96, 99, and 85 and 99%, respectively. In 39 of these 41 patients, CTCA assessment was concordant with the Medina lesion classification on ICA. Conclusion: Sixty-four-slice CTCA allows accurate assessment of complex BL.
KW - Bifurcations
KW - Computed tomography coronary angiography
KW - Coronary atherosclerosis
KW - Percutaneous coronary intervention
UR - https://www.scopus.com/pages/publications/35348921870
U2 - 10.1093/eurheartj/ehm195
DO - 10.1093/eurheartj/ehm195
M3 - Article
C2 - 17623681
AN - SCOPUS:35348921870
SN - 0195-668X
VL - 28
SP - 1968
EP - 1976
JO - European Heart Journal
JF - European Heart Journal
IS - 16
ER -
