TY - JOUR
T1 - Decreasing prevalence in cerebral palsy
T2 - A multi-site European population-based study, 1980 to 2003
AU - On behalf of surveillance of cerebral palsy network
AU - Sellier, Elodie
AU - Platt, Mary Jane
AU - Andersen, Guro L.
AU - Krägeloh-Mann, Ingeborg
AU - De La Cruz, Javier
AU - Cans, Christine
AU - Cans, C.
AU - Van Bakel, M.
AU - Arnaud, C.
AU - Delobel, M.
AU - Chalmers, J.
AU - McManus, V.
AU - Lyons, A.
AU - Parkes, J.
AU - Dolk, H.
AU - Himmelmann, K.
AU - Pahlman, M.
AU - Dowding, V.
AU - Colver, A.
AU - Pennington, L.
AU - Horridge, K.
AU - Kurinczuk, J.
AU - Surman, G.
AU - Platt, M. J.
AU - Udall, P.
AU - Rackauskaite, G.
AU - Torrioli, M. G.
AU - Marcelli, M.
AU - Andersen, G.
AU - Julsen Hollung, S.
AU - Bottos, M.
AU - Gaffney, G.
AU - De la Cruz, J.
AU - Pallas, C.
AU - Neubauer, D.
AU - Jekovec-Vrhovšek, M.
AU - Virella, D.
AU - Andrada, M.
AU - Greitane, A.
AU - Hollody, K.
AU - Sigurdardottir, S.
AU - Einarsson, I.
AU - Honold, M.
AU - Rostasy, K.
AU - Mejaski-Bosnjak, V.
N1 - Publisher Copyright:
© 2016 Mac Keith Press.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Aim: To monitor the trends in prevalence of cerebral palsy (CP) by birthweight in Europe, 1980 to 2003. Method: Data were collated from 20 population-based registers contributing to the Surveillance of Cerebral Palsy in Europe database. Trend analyses were conducted in four birthweight groups: <1000g (extremely low birthweight [ELBW]); 1000 to 1499g (very low birthweight [VLBW]); 1500 to 2499g (moderately low birthweight [MLBW]); and >2499g (normal birthweight [NBW]). Results: The overall prevalence of CP decreased from 1.90 to 1.77 per 1000 live births, p<0.001, with a mean annual fall of 0.7% (95% confidence interval [CI] -0.3% to -1.0%). Prevalence in NBW children showed a non-significant trend from 1.17 to 0.89 per 1000 live births (p=0.22). Prevalence in MLBW children decreased from 8.5 to 6.2 per 1000 live births (p<0.001), but not linearly. Prevalence in VLBW children also declined from 70.9 to 35.9 per 1000 live births (p<0.001) with a mean annual fall of 3.4% (95% CI -2.4% to -4.3%). Prevalence in ELBW children remained stable, at a mean rate of 42.4 per 1000 live births. Interpretation: The decline in prevalence of CP in children of VLBW continues, and confirms that previously reported. For the first time, there is also a significant decline among those of MLBW, resulting in a significant overall decrease in the prevalence of CP.
AB - Aim: To monitor the trends in prevalence of cerebral palsy (CP) by birthweight in Europe, 1980 to 2003. Method: Data were collated from 20 population-based registers contributing to the Surveillance of Cerebral Palsy in Europe database. Trend analyses were conducted in four birthweight groups: <1000g (extremely low birthweight [ELBW]); 1000 to 1499g (very low birthweight [VLBW]); 1500 to 2499g (moderately low birthweight [MLBW]); and >2499g (normal birthweight [NBW]). Results: The overall prevalence of CP decreased from 1.90 to 1.77 per 1000 live births, p<0.001, with a mean annual fall of 0.7% (95% confidence interval [CI] -0.3% to -1.0%). Prevalence in NBW children showed a non-significant trend from 1.17 to 0.89 per 1000 live births (p=0.22). Prevalence in MLBW children decreased from 8.5 to 6.2 per 1000 live births (p<0.001), but not linearly. Prevalence in VLBW children also declined from 70.9 to 35.9 per 1000 live births (p<0.001) with a mean annual fall of 3.4% (95% CI -2.4% to -4.3%). Prevalence in ELBW children remained stable, at a mean rate of 42.4 per 1000 live births. Interpretation: The decline in prevalence of CP in children of VLBW continues, and confirms that previously reported. For the first time, there is also a significant decline among those of MLBW, resulting in a significant overall decrease in the prevalence of CP.
UR - https://www.scopus.com/pages/publications/84955183799
U2 - 10.1111/dmcn.12865
DO - 10.1111/dmcn.12865
M3 - Article
C2 - 26330098
AN - SCOPUS:84955183799
SN - 0012-1622
VL - 58
SP - 85
EP - 92
JO - Developmental Medicine and Child Neurology
JF - Developmental Medicine and Child Neurology
IS - 1
ER -