TY - JOUR
T1 - Cross-resistance analysis for clinafloxacin compared with ciprofloxacin, fleroxacin, ofloxacin, and sparfloxacin using a predictor panel of ciprofloxacin-resistant bacteria
AU - Cormican, Martin G.
AU - Jones, Ronald N.
PY - 1995/8
Y1 - 1995/8
N2 - Clinafloxacin was significantly more active against fluoroquinolone-resistant organisms than ciprofloxacin, ofloxacin, sparfloxacin and fleroxacin. Clinafloxacin inhibited 65% of isolates at the recommended breakpoint (≦1mg/L)compared with only 30.0% for ciprofloxacin, 31.7% for ofloxacin, 32% for fleroxacin, and 37.7% for sparfloxacin at their recommended breakpoints. No strain susceptible to ciprofloxacin was resistant to the other compounds tested.
AB - Clinafloxacin was significantly more active against fluoroquinolone-resistant organisms than ciprofloxacin, ofloxacin, sparfloxacin and fleroxacin. Clinafloxacin inhibited 65% of isolates at the recommended breakpoint (≦1mg/L)compared with only 30.0% for ciprofloxacin, 31.7% for ofloxacin, 32% for fleroxacin, and 37.7% for sparfloxacin at their recommended breakpoints. No strain susceptible to ciprofloxacin was resistant to the other compounds tested.
UR - https://www.scopus.com/pages/publications/0029052824
U2 - 10.1093/jac/36.2.431
DO - 10.1093/jac/36.2.431
M3 - Article
C2 - 8522474
AN - SCOPUS:0029052824
SN - 0305-7453
VL - 36
SP - 431
EP - 434
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - 2
ER -