Comparison of plaque prolapse in consecutive patients treated with Xience v and Taxus Liberte stents

Jun Shen Zhu Jun Shen, Salvatore Brugaletta, Hector M. Garcia-Garcia, Jurgen Ligthart, Josep Gomez-Lara, Roberto Diletti, Giovanna Sarno, Karen Witberg, Patrick W. Serruys

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

9 Citations (Scopus)

Abstract

The purpose of this article is to investigate the prevalence of plaque prolapse (PP) after Xience V and Taxus Liberte stent implantation. During the study period 2006-2007, 200 consecutive patients underwent coronary revascularization for de novo lesions and received an intravascular ultrasound (IVUS) post-stenting evaluation, (n = 124 patients with Taxus Liberte and n = 76 with Xience V) (227 stent segments). Cross-sectional and longitudinal 3D IVUS images were analyzed in a blind fashion, evaluating the prevalence of PP and calculating its depth and angle. The angulation degree of the coronary artery at the lesion site pre-stent implantation was also evaluated by angiography. The prevalence of PP was 23.9% in Xience V versus 38.1% in Taxus Liberte (P = 0.025). The depth and angle of PP were greater in Taxus Liberte stent than Xience V stent (0.4 ± 0.1 mm versus 0.5 ± 0.2 mm, P = 0.004; and 32.0 ± 8.9° versus 44.6 ± 27.6°, P = 0.044, respectively). The angulation degree of the coronary artery at the lesion site was higher in presence of plaque prolapse than in its absence (48.2 ± 29.3° vs. 38.2 ± 28.1°, P = 0.013). By multivariate analysis, stent type was independently associated with incidence of plaque prolapse. Xience V stent has less plaque prolapse than Taxus Liberte stent. Stent design may play a role in the prevalence of plaque prolapse.

Original languageEnglish
Pages (from-to)23-31
Number of pages9
JournalInternational Journal of Cardiovascular Imaging
Volume28
Issue number1
DOIs
Publication statusPublished - Jan 2012
Externally publishedYes

Keywords

  • Drug eluting stent
  • IVUS
  • Plaque prolapse
  • Taxus Liberte stent
  • Xience V stent

Fingerprint

Dive into the research topics of 'Comparison of plaque prolapse in consecutive patients treated with Xience v and Taxus Liberte stents'. Together they form a unique fingerprint.

Cite this