Comparison of DNA replication in Xenopus laevis and Simian Virus 40

Maren Oehlmann; Cathal Mahon; Heinz Peter Nasheuer

doi:10.1007/978-0-387-69116-9_1

Comparison of DNA replication in Xenopus laevis and Simian Virus 40

Maren Oehlmann
, Cathal Mahon
, Heinz Peter Nasheuer

Molecular Biosciences

University of Galway

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

7 Citations (Scopus)

Abstract

DNA replication is a fundamental process within the cell cycle. The exact duplication of the genetic information ensures genome stability. Extensive research has identified the principal players required for the sequential processes: originlicensing (a controlled order of events giving a chromosome site the potential to be initiated within the S phase of the same cell cycle); initiation (by removing the license a previous licensed site is transformed into a site where the DNA helix starts to melt); and DNA replication (copying the parental DNA by leading and lagging strand DNA-synthesis). The present report compares the advantages and limitations of studying DNA replication in the model systems Xenopus laevis (X. laevis) and in Simian Virus 40 (SV40).

Original language	English
Title of host publication	Advances in Molecular Oncology
Subtitle of host publication	Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM)
Publisher	Springer New York
Pages	3-16
Number of pages	14
ISBN (Print)	9780387691145
DOIs	https://doi.org/10.1007/978-0-387-69116-9_1
Publication status	Published - 2007

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	604
ISSN (Print)	0065-2598

Access to Document

10.1007/978-0-387-69116-9_1

Cite this

Oehlmann, M., Mahon, C., & Nasheuer, H. P. (2007). Comparison of DNA replication in Xenopus laevis and Simian Virus 40. In Advances in Molecular Oncology: Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM) (pp. 3-16). (Advances in Experimental Medicine and Biology; Vol. 604). Springer New York. https://doi.org/10.1007/978-0-387-69116-9_1

Oehlmann, Maren ; Mahon, Cathal ; Nasheuer, Heinz Peter. / Comparison of DNA replication in Xenopus laevis and Simian Virus 40. Advances in Molecular Oncology: Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM). Springer New York, 2007. pp. 3-16 (Advances in Experimental Medicine and Biology).

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abstract = "DNA replication is a fundamental process within the cell cycle. The exact duplication of the genetic information ensures genome stability. Extensive research has identified the principal players required for the sequential processes: originlicensing (a controlled order of events giving a chromosome site the potential to be initiated within the S phase of the same cell cycle); initiation (by removing the license a previous licensed site is transformed into a site where the DNA helix starts to melt); and DNA replication (copying the parental DNA by leading and lagging strand DNA-synthesis). The present report compares the advantages and limitations of studying DNA replication in the model systems Xenopus laevis (X. laevis) and in Simian Virus 40 (SV40).",

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Oehlmann, M, Mahon, C & Nasheuer, HP 2007, Comparison of DNA replication in Xenopus laevis and Simian Virus 40. in Advances in Molecular Oncology: Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM). Advances in Experimental Medicine and Biology, vol. 604, Springer New York, pp. 3-16. https://doi.org/10.1007/978-0-387-69116-9_1

Comparison of DNA replication in Xenopus laevis and Simian Virus 40. / Oehlmann, Maren; Mahon, Cathal; Nasheuer, Heinz Peter.
Advances in Molecular Oncology: Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM). Springer New York, 2007. p. 3-16 (Advances in Experimental Medicine and Biology; Vol. 604).

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

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N2 - DNA replication is a fundamental process within the cell cycle. The exact duplication of the genetic information ensures genome stability. Extensive research has identified the principal players required for the sequential processes: originlicensing (a controlled order of events giving a chromosome site the potential to be initiated within the S phase of the same cell cycle); initiation (by removing the license a previous licensed site is transformed into a site where the DNA helix starts to melt); and DNA replication (copying the parental DNA by leading and lagging strand DNA-synthesis). The present report compares the advantages and limitations of studying DNA replication in the model systems Xenopus laevis (X. laevis) and in Simian Virus 40 (SV40).

AB - DNA replication is a fundamental process within the cell cycle. The exact duplication of the genetic information ensures genome stability. Extensive research has identified the principal players required for the sequential processes: originlicensing (a controlled order of events giving a chromosome site the potential to be initiated within the S phase of the same cell cycle); initiation (by removing the license a previous licensed site is transformed into a site where the DNA helix starts to melt); and DNA replication (copying the parental DNA by leading and lagging strand DNA-synthesis). The present report compares the advantages and limitations of studying DNA replication in the model systems Xenopus laevis (X. laevis) and in Simian Virus 40 (SV40).

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Oehlmann M, Mahon C, Nasheuer HP. Comparison of DNA replication in Xenopus laevis and Simian Virus 40. In Advances in Molecular Oncology: Edited under the auspices of the European Institute of Oncology (IEO) and The FIRC Institute of Molecular Oncology Foundation (IFOM). Springer New York. 2007. p. 3-16. (Advances in Experimental Medicine and Biology). doi: 10.1007/978-0-387-69116-9_1

Comparison of DNA replication in Xenopus laevis and Simian Virus 40

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