TY - JOUR
T1 - Cognitive performance in presumed obligate carriers for psychosis
AU - Toulopoulou, Timothea
AU - Mapua-Filbey, Francesca
AU - Quraishi, Seema
AU - Kravariti, Eugenia
AU - Morris, Robin G.
AU - McDonald, Colm
AU - Walshe, Muriel
AU - Bramon, Elvira
AU - Murray, Robin M.
PY - 2005/9
Y1 - 2005/9
N2 - We report cognitive performance of a group of individuals who are likely to have transmitted liability to psychosis to their offspring. Out of 230 relatives of patients with psychosis, 27 met our criteria for a presumed obligate carrier, that is a non-psychotic individual who had a parent or a sibling as well as an offspring with psychosis. The presumed obligate carriers showed impairments in verbal memory and in visuospatial manipulations, suggesting that these individuals transmit vulnerability for psychosis to their offspring in terms of a disability to recall verbal information and an impaired capacity to perceive spatial relations.
AB - We report cognitive performance of a group of individuals who are likely to have transmitted liability to psychosis to their offspring. Out of 230 relatives of patients with psychosis, 27 met our criteria for a presumed obligate carrier, that is a non-psychotic individual who had a parent or a sibling as well as an offspring with psychosis. The presumed obligate carriers showed impairments in verbal memory and in visuospatial manipulations, suggesting that these individuals transmit vulnerability for psychosis to their offspring in terms of a disability to recall verbal information and an impaired capacity to perceive spatial relations.
UR - https://www.scopus.com/pages/publications/24944470296
U2 - 10.1192/bjp.187.3.284
DO - 10.1192/bjp.187.3.284
M3 - Article
SN - 0007-1250
VL - 187
SP - 284
EP - 285
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
IS - SEPT.
ER -