Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Michael Cassidy; Charles E. Connolly

doi:10.1017/S0022215100127331

Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Michael Cassidy
, Charles E. Connolly

University College Hospital

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

16 Citations (Scopus)

Abstract

Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

Original language	English
Pages (from-to)	529-532
Number of pages	4
Journal	The Journal of Laryngology & Otology
Volume	108
Issue number	6
DOIs	https://doi.org/10.1017/S0022215100127331
Publication status	Published - Jun 1994
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Carcinoma
clear cell
Ploidies
Salivary gland neoplasms

Access to Document

10.1017/S0022215100127331

Cite this

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title = "Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland",

abstract = "Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.",

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AU - Cassidy, Michael

AU - Connolly, Charles E.

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N2 - Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

AB - Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

KW - Carcinoma

KW - clear cell

KW - Ploidies

KW - Salivary gland neoplasms

UR - https://www.scopus.com/pages/publications/0028363346

U2 - 10.1017/S0022215100127331

DO - 10.1017/S0022215100127331

M3 - Article

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AN - SCOPUS:0028363346

SN - 0022-2151

VL - 108

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EP - 532

JO - The Journal of Laryngology & Otology

JF - The Journal of Laryngology & Otology

IS - 6

ER -

Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Abstract

UN SDGs

Keywords

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