Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Michael Cassidy; Charles E. Connolly

doi:10.1017/S0022215100127331

Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Michael Cassidy, Charles E. Connolly

University College Hospital

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

16 Citations (Scopus)

Abstract

Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

Original language	English
Pages (from-to)	529-532
Number of pages	4
Journal	The Journal of Laryngology & Otology
Volume	108
Issue number	6
DOIs	https://doi.org/10.1017/S0022215100127331
Publication status	Published - Jun 1994
Externally published	Yes

Keywords

Carcinoma
clear cell
Ploidies
Salivary gland neoplasms

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/S0022215100127331

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abstract = "Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.",

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AB - Clear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbB-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

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KW - Ploidies

KW - Salivary gland neoplasms

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Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

Abstract

Keywords

UN SDGs

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