Chemical structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide

Orla M. Hanniffy; Alexander S. Shashkov; Anthony P. Moran; Sof'ya N. Senchenkova; Angela V. Savage

doi:10.1016/S0008-6215(00)00281-0

Chemical structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide

Orla M. Hanniffy
, Alexander S. Shashkov
, Anthony P. Moran
, Sof'ya N. Senchenkova
, Angela V. Savage

Cellular & Molecular Medicine

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

8 Citations (Scopus)

Abstract

The structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide was determined and found to contain 3-deoxy-D-manno-octulosonic acid (Kdo), L-glycero-D-manno-heptose (LD-Hep), D-galactose, D-glucose, and phosphorylethanolamine (PEtn). Based on ¹H, ¹³C and ³¹P NMR spectroscopic studies including 2D COSY, TOCSY, ROESY and heteronuclear ¹H-³¹P and HMQC experiments it was established that the oligosaccharide has the following structure:

Original language	English
Pages (from-to)	223-229
Number of pages	7
Journal	Carbohydrate Research
Volume	330
Issue number	2
DOIs	https://doi.org/10.1016/S0008-6215(00)00281-0
Publication status	Published - 30 Jan 2001

Keywords

Aerotolerant O:2 core oligosaccharide, structure
Campylobacter jejuni
NMR spectroscopy

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10.1016/S0008-6215(00)00281-0

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title = "Chemical structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide",

abstract = "The structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide was determined and found to contain 3-deoxy-D-manno-octulosonic acid (Kdo), L-glycero-D-manno-heptose (LD-Hep), D-galactose, D-glucose, and phosphorylethanolamine (PEtn). Based on 1H, 13C and 31P NMR spectroscopic studies including 2D COSY, TOCSY, ROESY and heteronuclear 1H-31P and HMQC experiments it was established that the oligosaccharide has the following structure:",

keywords = "Aerotolerant O:2 core oligosaccharide, structure, Campylobacter jejuni, NMR spectroscopy",

author = "Hanniffy, \{Orla M.\} and Shashkov, \{Alexander S.\} and Moran, \{Anthony P.\} and Senchenkova, \{Sof'ya N.\} and Savage, \{Angela V.\}",

year = "2001",

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doi = "10.1016/S0008-6215(00)00281-0",

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T1 - Chemical structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide

AU - Hanniffy, Orla M.

AU - Shashkov, Alexander S.

AU - Moran, Anthony P.

AU - Senchenkova, Sof'ya N.

AU - Savage, Angela V.

PY - 2001/1/30

Y1 - 2001/1/30

N2 - The structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide was determined and found to contain 3-deoxy-D-manno-octulosonic acid (Kdo), L-glycero-D-manno-heptose (LD-Hep), D-galactose, D-glucose, and phosphorylethanolamine (PEtn). Based on 1H, 13C and 31P NMR spectroscopic studies including 2D COSY, TOCSY, ROESY and heteronuclear 1H-31P and HMQC experiments it was established that the oligosaccharide has the following structure:

AB - The structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide was determined and found to contain 3-deoxy-D-manno-octulosonic acid (Kdo), L-glycero-D-manno-heptose (LD-Hep), D-galactose, D-glucose, and phosphorylethanolamine (PEtn). Based on 1H, 13C and 31P NMR spectroscopic studies including 2D COSY, TOCSY, ROESY and heteronuclear 1H-31P and HMQC experiments it was established that the oligosaccharide has the following structure:

KW - Aerotolerant O:2 core oligosaccharide, structure

KW - Campylobacter jejuni

KW - NMR spectroscopy

UR - https://www.scopus.com/pages/publications/0035969927

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DO - 10.1016/S0008-6215(00)00281-0

M3 - Article

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AN - SCOPUS:0035969927

SN - 0008-6215

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JO - Carbohydrate Research

JF - Carbohydrate Research

IS - 2

ER -

Chemical structure of the core oligosaccharide of aerotolerant Campylobacter jejuni O:2 lipopolysaccharide

Abstract

Keywords

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