Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms

Dandan Li; You-Jun Fu; James F. Rusling

doi:10.13025/28910

Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms

Dandan Li
, You-Jun Fu
, James F. Rusling

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

3 Citations (Scopus)

Abstract

We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.

Original language	English (Ireland)
Journal	Chemical Communications
DOIs	https://doi.org/10.13025/28910 https://doi.org/10.1039/c5cc00420a
Publication status	Published - 1 Jan 2015
Externally published	Yes

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10.13025/28910Licence: CC BY-NC-ND
10.1039/c5cc00420a

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title = "Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms",

abstract = "We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.",

author = "Dandan Li and You-Jun Fu and Rusling, \{James F.\}",

year = "2015",

month = jan,

day = "1",

doi = "10.13025/28910",

language = "English (Ireland)",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms

AU - Li, Dandan

AU - Fu, You-Jun

AU - Rusling, James F.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.

AB - We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.

UR - http://hdl.handle.net/10379/12441

U2 - 10.13025/28910

DO - 10.13025/28910

M3 - Article

SN - 1359-7345

JO - Chemical Communications

JF - Chemical Communications

ER -

Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms

Abstract

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