Cell and cell sheet recovery from pNIPAm coatings; Motivation and history to present day approaches

Maria E. Nash; Deirdre Healy; William M. Carroll; Carlos Elvira; Yury A. Rochev

doi:10.1039/c2jm31748f

Cell and cell sheet recovery from pNIPAm coatings; Motivation and history to present day approaches

Maria E. Nash
, Deirdre Healy
, William M. Carroll
, Carlos Elvira
, Yury A. Rochev

Biomedical Engineering

CSIC - Instituto de Ciencia y Tecnologia de Polimeros (ICTP)
University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review

107 Citations (Scopus)

Abstract

The regeneration of cells and cell sheets mediated by thermoresponsive substrates represents an important and ever growing area in tissue engineering. This review seeks to track the development of this field from inception to the present day by highlighting the most significant breakthroughs as well as focusing on important physical and chemical characterization of substrates produced for this specific purpose. Furthermore, a critical evaluation encompassing the advantages and disadvantages of different techniques used for producing such surfaces will be included as well as suggestions for possible future directions.

Original language	English
Pages (from-to)	19376-19389
Number of pages	14
Journal	Journal of Materials Chemistry
Volume	22
Issue number	37
DOIs	https://doi.org/10.1039/c2jm31748f
Publication status	Published - 7 Oct 2012

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10.1039/c2jm31748f

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abstract = "The regeneration of cells and cell sheets mediated by thermoresponsive substrates represents an important and ever growing area in tissue engineering. This review seeks to track the development of this field from inception to the present day by highlighting the most significant breakthroughs as well as focusing on important physical and chemical characterization of substrates produced for this specific purpose. Furthermore, a critical evaluation encompassing the advantages and disadvantages of different techniques used for producing such surfaces will be included as well as suggestions for possible future directions.",

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AB - The regeneration of cells and cell sheets mediated by thermoresponsive substrates represents an important and ever growing area in tissue engineering. This review seeks to track the development of this field from inception to the present day by highlighting the most significant breakthroughs as well as focusing on important physical and chemical characterization of substrates produced for this specific purpose. Furthermore, a critical evaluation encompassing the advantages and disadvantages of different techniques used for producing such surfaces will be included as well as suggestions for possible future directions.

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Cell and cell sheet recovery from pNIPAm coatings; Motivation and history to present day approaches

Abstract

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