British Society for Matrix Biology Spring 2019 Meeting: Stroma, Niche, Repair

Eugenia Pugliese; Dimitrios I. Zeugolis

doi:10.13025/20871

British Society for Matrix Biology Spring 2019 Meeting: Stroma, Niche, Repair

Eugenia Pugliese
, Dimitrios I. Zeugolis

Mechanical Engineering

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

1 Citation (Scopus)

Abstract

The enthesis is a specialised tissue interface between tendon and bone, essential for adequate force transmission. Following injuries and surgical repair, the enthesis is often not re-established and traditionally used tissue substitutes have lacked to reproduce the complexity of the native tissue. We hypothesised that a collagen-based three-layer scaffold that mimic the composition of the enthesis, in combination with bioactive molecules, will enhance the functional regeneration of the tissue.

Original language	English (Ireland)
Title of host publication	BSMB Spring Meeting Stroma, Niche and Repair
Publisher	wiley
DOIs	https://doi.org/10.13025/20871 https://doi.org/10.1111/iep.12332
Publication status	Published - 1 Apr 2019

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10.13025/20871Licence: CC BY-NC-ND
10.1111/iep.12332

EAccepted author manuscript, 98.7 KBLicence: CC BY-NC-ND

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abstract = "The enthesis is a specialised tissue interface between tendon and bone, essential for adequate force transmission. Following injuries and surgical repair, the enthesis is often not re-established and traditionally used tissue substitutes have lacked to reproduce the complexity of the native tissue. We hypothesised that a collagen-based three-layer scaffold that mimic the composition of the enthesis, in combination with bioactive molecules, will enhance the functional regeneration of the tissue.",

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AB - The enthesis is a specialised tissue interface between tendon and bone, essential for adequate force transmission. Following injuries and surgical repair, the enthesis is often not re-established and traditionally used tissue substitutes have lacked to reproduce the complexity of the native tissue. We hypothesised that a collagen-based three-layer scaffold that mimic the composition of the enthesis, in combination with bioactive molecules, will enhance the functional regeneration of the tissue.

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British Society for Matrix Biology Spring 2019 Meeting: Stroma, Niche, Repair

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