Bone mechanical properties and changes with osteoporosis

Georg Osterhoff; Elise F. Morgan; Sandra J. Shefelbine; Lamya Karim; Laoise M. McNamara; Peter Augat

doi:10.13025/28625

Bone mechanical properties and changes with osteoporosis

Georg Osterhoff
, Elise F. Morgan
, Sandra J. Shefelbine
, Lamya Karim
, Laoise M. McNamara
, Peter Augat

Biomedical Engineering

University of British Columbia
Boston University College of Engineering
Northeastern University
Harvard Medical School
Trauma Center Murnau
Paracelsus Medical University

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

521 Citations (Scopus)

Abstract

This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.

Original language	English
Pages (from-to)	S11-S20
Journal	Injury
Volume	47
DOIs	https://doi.org/10.13025/28625 https://doi.org/10.1016/s0020-1383(16)47003-8
Publication status	Published - 1 Jun 2016

Keywords

Biomechanics
Bone fragility
Bone loss
Bone resorption
Collagen

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10.13025/28625Licence: CC BY-NC-ND
10.1016/s0020-1383(16)47003-8

Cite this

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title = "Bone mechanical properties and changes with osteoporosis",

abstract = "This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.",

keywords = "Biomechanics, Bone fragility, Bone loss, Bone resorption, Collagen",

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AU - Osterhoff, Georg

AU - Morgan, Elise F.

AU - Shefelbine, Sandra J.

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AU - McNamara, Laoise M.

AU - Augat, Peter

PY - 2016/6/1

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N2 - This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.

AB - This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.

KW - Biomechanics

KW - Bone fragility

KW - Bone loss

KW - Bone resorption

KW - Collagen

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JO - Injury

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Bone mechanical properties and changes with osteoporosis

Abstract

Keywords

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