Bipolar patients taking lithium have increased dark adaptation threshold compared with controls

P. A. Carney, J. Seggie, M. Vojtechovsky, J. Parker, E. Grof, P. Grof

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

11 Citations (Scopus)

Abstract

Recent epidemiological studies of mania suggest that admissions correlate with length of day and sunlight. As well, seasonal affective disorder - a depression occuring in winter, is reported to respond to light therapy and it has been proposed that supersensitivity to light is a trait-marker of manic-depressive illness. Dark adaptation threshold (D.A.T.) - a measure of night vision - was assessed in 19 euthymic manic-depressive patients stabilized on lithium, and in 19 drug-free healthy controls. The D.A.T. was significantly raised in the patients taking lithium. It is concluded that lithium induces subsensitivity to light.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalPharmacopsychiatry
Volume21
Issue number3
DOIs
Publication statusPublished - 1988
Externally publishedYes

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