TY - JOUR
T1 - Bioresorbable scaffolds
T2 - Current knowledge, potentialities and limitations experienced during their first clinical applications
AU - Bourantas, Christos V.
AU - Onuma, Yoshinobu
AU - Farooq, Vasim
AU - Zhang, Yaojun
AU - Garcia-Garcia, Hector M.
AU - Serruys, Patrick W.
PY - 2013/7/15
Y1 - 2013/7/15
N2 - The traditional metallic stents have significant limitations as they predispose to late thrombosis, may preclude surgical revascularization and distort vessel physiology. Bioresorbable scaffolds (BRSs) are a relatively new technology introduced to overcome these drawbacks. The potential of these devices as well as the reported results from their clinical applications attracted interest and drove research and industry towards the development of new BRSs and the improvement of the existing devices. Thus, over the last years considerable progress has been made and today numerous BRSs are available. The aim of this review article is to highlight the potentialities of these devices, describe the evidence from the recent clinical trials and discuss the advantages, limitations and concerns that were aroused during the first implementation of BRSs in clinical arena.
AB - The traditional metallic stents have significant limitations as they predispose to late thrombosis, may preclude surgical revascularization and distort vessel physiology. Bioresorbable scaffolds (BRSs) are a relatively new technology introduced to overcome these drawbacks. The potential of these devices as well as the reported results from their clinical applications attracted interest and drove research and industry towards the development of new BRSs and the improvement of the existing devices. Thus, over the last years considerable progress has been made and today numerous BRSs are available. The aim of this review article is to highlight the potentialities of these devices, describe the evidence from the recent clinical trials and discuss the advantages, limitations and concerns that were aroused during the first implementation of BRSs in clinical arena.
KW - Bioresorbable scaffolds
KW - Coronary artery disease
KW - Drug eluting stents
UR - http://www.scopus.com/inward/record.url?scp=84878529444&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2012.05.093
DO - 10.1016/j.ijcard.2012.05.093
M3 - Review article
C2 - 22748288
AN - SCOPUS:84878529444
SN - 0167-5273
VL - 167
SP - 11
EP - 21
JO - International Journal of Cardiology
JF - International Journal of Cardiology
IS - 1
ER -
