Bioactive guanidine alkaloids from two caribbean marine sponges

Rémi Laville; Olivier P. Thomas; Fabrice Berrué; Diana Marquez; Jean Vacelet; Philippe Amade

doi:10.1021/np900244g

Bioactive guanidine alkaloids from two caribbean marine sponges

Rémi Laville, Olivier P. Thomas, Fabrice Berrué, Diana Marquez, Jean Vacelet, Philippe Amade

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

74 Citations (Scopus)

Abstract

Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.

Original language	English
Pages (from-to)	1589-1594
Number of pages	6
Journal	Journal of Natural Products
Volume	72
Issue number	9
DOIs	https://doi.org/10.1021/np900244g
Publication status	Published - 25 Sep 2009
Externally published	Yes

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10.1021/np900244g

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abstract = "Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.",

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T1 - Bioactive guanidine alkaloids from two caribbean marine sponges

AU - Laville, Rémi

AU - Thomas, Olivier P.

AU - Berrué, Fabrice

AU - Marquez, Diana

AU - Vacelet, Jean

AU - Amade, Philippe

PY - 2009/9/25

Y1 - 2009/9/25

N2 - Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.

AB - Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.

UR - https://www.scopus.com/pages/publications/70349499191

U2 - 10.1021/np900244g

DO - 10.1021/np900244g

M3 - Article

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JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 9

ER -

Bioactive guanidine alkaloids from two caribbean marine sponges

Abstract

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