Abstract
Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.
| Original language | English (Ireland) |
|---|---|
| Pages (from-to) | 311-313 |
| Number of pages | 3 |
| Journal | European Psychiatry |
| Volume | 25 |
| Issue number | 66 |
| Publication status | Published - 1 Oct 2010 |
Keywords
- Aggression
- BDNF
- Polymorphism
- Schizophrenia
- Val66Met
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Spalletta, G.,Morris, D. W.,Angelucci, F.,Rubino, I. A.,Spoletini, I.,Bria, P.,Martinotti, G.,Siracusano, A.,Bonaviri, G.,Bernardini, S.,Caltagirone, C.,Bossu, P.,Donohoe, G.,Gill, M.,Corvin, A. P.