Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis

A. W. O'Regan; C. Castro; S. A. Lukehart; J. M. Kasznica; P. A. Rice; M. F. Joyce-Brady

doi:10.1136/thorax.57.10.917

Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis

A. W. O'Regan, C. Castro, S. A. Lukehart, J. M. Kasznica, P. A. Rice, M. F. Joyce-Brady

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

29 Citations (Scopus)

Abstract

The presentation of syphilitic aortitis is often atypical and available serological tests are non-specific. The diagnostic gold standard remains direct identification of microorganisms in tissue. We present a case of syphilitic aortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease.

Original language	English
Pages (from-to)	917-918
Number of pages	2
Journal	Thorax
Volume	57
Issue number	10
DOIs	https://doi.org/10.1136/thorax.57.10.917
Publication status	Published - 1 Oct 2002
Externally published	Yes

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10.1136/thorax.57.10.917

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AU - Kasznica, J. M.

AU - Rice, P. A.

AU - Joyce-Brady, M. F.

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AB - The presentation of syphilitic aortitis is often atypical and available serological tests are non-specific. The diagnostic gold standard remains direct identification of microorganisms in tissue. We present a case of syphilitic aortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease.

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Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis

Abstract

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