Arterial and Atherosclerotic Plaque Biomechanics with Application to Stent Angioplasty Modeling

Brían L. O’Reilly, Claire Conway, J. Patrick McGarry, Peter E. McHugh

Research output: Chapter in Book or Conference Publication/ProceedingChapterpeer-review

1 Citation (Scopus)

Abstract

This chapter provides a brief review of continuum mechanics in relation to application in vascular biomechanics. The initial focus is on arterial tissue, where fundamental constitutive representations, tissue anisotropy, tissue remodeling and damage modeling are overviewed. The focus then shifts to diseased tissue (atherosclerotic plaque tissue), where experimental mechanical characterization, and constitutive and damage modeling are reviewed. Conclusions are drawn on what has been achieved thus far, and the main challenges for the future in characterizing and modeling this complex tissue are identified. Finally, the application of the arterial mechanics in the computational modeling of the stent angioplasty procedure is considered, with future challenges identified.

Original languageEnglish
Title of host publicationStudies in Mechanobiology, Tissue Engineering and Biomaterials
PublisherSpringer
Pages193-231
Number of pages39
DOIs
Publication statusPublished - 2017

Publication series

NameStudies in Mechanobiology, Tissue Engineering and Biomaterials
Volume20
ISSN (Print)1868-2006
ISSN (Electronic)1868-2014

Keywords

  • Arterial Tissue
  • Continuum Damage Mechanic
  • Mullins Effect
  • Plaque Tissue
  • Rupture Stress

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