Abstract
In this study of 500 patients with breast carcinoma, we have prospectively assessed the role of preoperative CA 15-3 as a marker of disease burden over a 7 year period. CA 15-3 levels at presentation correlate with stage of disease, tumour size, lymph node status, the presence of metastases and lymphocyte infiltration into the tumour. CA 15-3 alone is not an independent prognostic indicator, although a serum level of 40 U ml(-1) has a positive predictive value of 83% for the presence of advanced disease. We recommend the routine use of this marker in the preoperative assessment of primary breast carcinoma.
| Original language | English (Ireland) |
|---|---|
| Number of pages | 3 |
| Journal | British Journal Of Cancer |
| Volume | 71 |
| Publication status | Published - 1 Jun 1995 |
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- OHANLON, DM;KERIN, MJ;KENT, P;MAHER, D;GRIMES, H;GIVEN, HF
