An analysis of challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder in Fragile X Syndrome

Isabel Newman, Geraldine Leader, June L. Chen, Arlene Mannion

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

38 Citations (Scopus)

Abstract

The present study sought to investigate the relationship between challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder (AD/HD) in Fragile X Syndrome (FRAX). Additionally, this study sought to examine how such disorders are predicted by gender, presence of autism spectrum disorder (ASD), and presence of intellectual disability (ID). A total of 47 children and adolescents with FRAX were assessed. Results revealed high levels of challenging behavior and AD/HD symptoms within the sample, with some participants exhibiting symptoms of comorbid psychopathology. Further analysis revealed that challenging behavior and comorbid psychopathology were positively correlated, with stereotypy correlating most strongly with comorbid psychopathology. In addition, ASD was found to predict challenging behavior, and gender was found to predict AD/HD symptoms. The implications of these findings are discussed.

Original languageEnglish
Pages (from-to)7-17
Number of pages11
JournalResearch in Developmental Disabilities
Volume38
DOIs
Publication statusPublished - 1 Mar 2015

Keywords

  • Attention-Deficit/Hyperactivity Disorder
  • Challenging behavior
  • Comorbid psychopathology
  • Comorbidity
  • Fragile X Syndrome

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