Advancements and Challenges in Multidomain Multicargo Delivery Vehicles

Eugenia Pugliese; João Q. Coentro; Dimitrios I. Zeugolis

doi:10.1002/adma.201704324

Advancements and Challenges in Multidomain Multicargo Delivery Vehicles

Eugenia Pugliese
, João Q. Coentro
, Dimitrios I. Zeugolis

University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

37 Citations (Scopus)

Abstract

Reparative and regenerative processes are well-orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer-by-layer, composite, self-assembly, and core–shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.

Original language	English
Article number	1704324
Journal	Advanced Materials
Volume	30
Issue number	13
DOIs	https://doi.org/10.1002/adma.201704324
Publication status	Published - 27 Mar 2018
Externally published	Yes

Keywords

coaxial electrospinning/electrospraying
dendrimers/polymersomes/micelles/liposomes
multicompartment biomaterials
multidrug/gene/cell delivery

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10.1002/adma.201704324

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title = "Advancements and Challenges in Multidomain Multicargo Delivery Vehicles",

abstract = "Reparative and regenerative processes are well-orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer-by-layer, composite, self-assembly, and core–shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.",

keywords = "coaxial electrospinning/electrospraying, dendrimers/polymersomes/micelles/liposomes, multicompartment biomaterials, multidrug/gene/cell delivery",

author = "Eugenia Pugliese and Coentro, \{Jo{\~a}o Q.\} and Zeugolis, \{Dimitrios I.\}",

note = "Publisher Copyright: {\textcopyright} 2018 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2018",

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doi = "10.1002/adma.201704324",

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AU - Pugliese, Eugenia

AU - Coentro, João Q.

AU - Zeugolis, Dimitrios I.

PY - 2018/3/27

Y1 - 2018/3/27

N2 - Reparative and regenerative processes are well-orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer-by-layer, composite, self-assembly, and core–shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.

AB - Reparative and regenerative processes are well-orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer-by-layer, composite, self-assembly, and core–shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.

KW - coaxial electrospinning/electrospraying

KW - dendrimers/polymersomes/micelles/liposomes

KW - multicompartment biomaterials

KW - multidrug/gene/cell delivery

UR - https://www.scopus.com/pages/publications/85042011431

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DO - 10.1002/adma.201704324

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VL - 30

JO - Advanced Materials

JF - Advanced Materials

IS - 13

M1 - 1704324

ER -

Advancements and Challenges in Multidomain Multicargo Delivery Vehicles

Abstract

Keywords

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