Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly

Jose C. Casas-Martinez; Qin Xia; Penglin Li; Maria Borja-Gonzalez; Antonio Miranda-Vizuete; Emma McDermott; Peter Dockery; Leo R. Quinlan; Katarzyna Goljanek-Whysall; Afshin Samali; Brian McDonagh

doi:10.1038/s41418-025-01603-7

Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly

Jose C. Casas-Martinez
, Qin Xia
, Penglin Li
, Maria Borja-Gonzalez
, Antonio Miranda-Vizuete
, Emma McDermott
, Peter Dockery
, Leo R. Quinlan
, Katarzyna Goljanek-Whysall
, Afshin Samali
, Brian McDonagh

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

3 Citations (Scopus)

Original language	Undefined/Unknown
Journal	Cell Death & Differentiation
DOIs	https://doi.org/10.1038/s41418-025-01603-7
Publication status	Published - 1 Nov 2025

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10.1038/s41418-025-01603-7

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title = "Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly",

author = "Casas-Martinez, \{Jose C.\} and Qin Xia and Penglin Li and Maria Borja-Gonzalez and Antonio Miranda-Vizuete and Emma McDermott and Peter Dockery and Quinlan, \{Leo R.\} and Katarzyna Goljanek-Whysall and Afshin Samali and Brian McDonagh",

year = "2025",

month = nov,

day = "1",

doi = "10.1038/s41418-025-01603-7",

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journal = "Cell Death \& Differentiation",

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TY - JOUR

T1 - Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly

AU - Casas-Martinez, Jose C.

AU - Xia, Qin

AU - Li, Penglin

AU - Borja-Gonzalez, Maria

AU - Miranda-Vizuete, Antonio

AU - McDermott, Emma

AU - Dockery, Peter

AU - Quinlan, Leo R.

AU - Goljanek-Whysall, Katarzyna

AU - Samali, Afshin

AU - McDonagh, Brian

PY - 2025/11/1

Y1 - 2025/11/1

UR - https://doi.org/10.1038/s41418-025-01603-7

U2 - 10.1038/s41418-025-01603-7

DO - 10.1038/s41418-025-01603-7

M3 - Article

JO - Cell Death & Differentiation

JF - Cell Death & Differentiation

ER -

Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly

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