Acute haemodynamic effects of the β1-adrenoceptor partial agonist xamoterol at rest and during supine exercise in patients with left ventricular dysfunction due to ischaemic heart disease: A double-blind randomized trial

P. J. De Feyter; P. W. Serruys

doi:10.1093/eurheartj/11.suppl_a.48

Acute haemodynamic effects of the β₁-adrenoceptor partial agonist xamoterol at rest and during supine exercise in patients with left ventricular dysfunction due to ischaemic heart disease: A double-blind randomized trial

P. J. De Feyter, P. W. Serruys

Erasmus University Rotterdam

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

2 Citations (Scopus)

Abstract

The effects of xamoterol 0.2 mg kg^-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidence of worsening myocardial ischaemia.

Original language	English
Pages (from-to)	48-49
Number of pages	2
Journal	European Heart Journal
Volume	11
Issue number	SUPPL. A
DOIs	https://doi.org/10.1093/eurheartj/11.suppl_a.48
Publication status	Published - 1990
Externally published	Yes

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abstract = "The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50\% of maximal exercise, without evidence of worsening myocardial ischaemia.",

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Acute haemodynamic effects of the β₁-adrenoceptor partial agonist xamoterol at rest and during supine exercise in patients with left ventricular dysfunction due to ischaemic heart disease: A double-blind randomized trial. / De Feyter, P. J.; Serruys, P. W.
In: European Heart Journal, Vol. 11, No. SUPPL. A, 1990, p. 48-49.

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

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AB - The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidence of worsening myocardial ischaemia.

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