Abstract
An approach to resorcylic acid lactones is described, exploiting an intramolecular olefination reaction for the generation of the 14-membered macrolactone. The synthetic route gave zearalenone precursors, and the preparations of other RAL analogues, trans- and cis-resorcylides are included, the latter being prepared by photoisomerization of the trans-isomer. beta-Haloketone derivatives were also prepared in a highly stereoselective manner by conjugate addition of chloride or bromide to the E-enone using boron trichloride and boron tribromide, respectively.
| Original language | English (Ireland) |
|---|---|
| Pages (from-to) | 7404-7407 |
| Number of pages | 4 |
| Journal | Journal Of Organic Chemistry |
| Volume | 75 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 1 Nov 2010 |
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Napolitano, C,McArdle, P,Murphy, PV
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