A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities

Leila Tabrizi; Hossein Chiniforoshan; Patrick McArdle

doi:10.1016/j.saa.2014.12.072

A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities

Leila Tabrizi
, Hossein Chiniforoshan
, Patrick McArdle

Isfahan University of Technology
University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

10 Citations (Scopus)

Abstract

A novel 1D coordination polymer {[Mn(μ_1,5-dca)₂(PZA)₂](PZA)₂}_n, 1, has been synthesized and characterized by single crystal X-ray crystallography. The coordination mode of dicyanamide (dca) and pyrazinamide (PZA) ligands was inferred by IR spectroscopy. The compound 1 was evaluated for in vitro antimycobacterial and antitumor activities. It demonstrated better in vitro activity against Mycobacterium tuberculosis than pyrazinamide and its MIC value was determined. Complex 1 was also screened for its in vitro antitumor activity towards LM3 and LP07 murine cancer cell lines. In addition, the antibacterial activity of complex 1 has been tested against Gram(+) and Gram(-) bacteria and it has shown promising broad range anti-bacterial activity.

Original language	English
Pages (from-to)	307-312
Number of pages	6
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	139
DOIs	https://doi.org/10.1016/j.saa.2014.12.072
Publication status	Published - 15 Mar 2015
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antibacterial activity
Antitumor activity
Dicyanamide
Manganese(II)
Pyrazinamide

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Tabrizi, L., Chiniforoshan, H., & McArdle, P. (2015). A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 139, 307-312. https://doi.org/10.1016/j.saa.2014.12.072

Tabrizi, Leila ; Chiniforoshan, Hossein ; McArdle, Patrick. / A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands : Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities. In: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2015 ; Vol. 139. pp. 307-312.

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title = "A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities",

abstract = "A novel 1D coordination polymer \{[Mn(μ1,5-dca)2(PZA)2](PZA)2\}n, 1, has been synthesized and characterized by single crystal X-ray crystallography. The coordination mode of dicyanamide (dca) and pyrazinamide (PZA) ligands was inferred by IR spectroscopy. The compound 1 was evaluated for in vitro antimycobacterial and antitumor activities. It demonstrated better in vitro activity against Mycobacterium tuberculosis than pyrazinamide and its MIC value was determined. Complex 1 was also screened for its in vitro antitumor activity towards LM3 and LP07 murine cancer cell lines. In addition, the antibacterial activity of complex 1 has been tested against Gram(+) and Gram(-) bacteria and it has shown promising broad range anti-bacterial activity.",

keywords = "Antibacterial activity, Antitumor activity, Dicyanamide, Manganese(II), Pyrazinamide",

author = "Leila Tabrizi and Hossein Chiniforoshan and Patrick McArdle",

year = "2015",

month = mar,

day = "15",

doi = "10.1016/j.saa.2014.12.072",

language = "English",

volume = "139",

pages = "307--312",

journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",

issn = "1386-1425",

publisher = "Elsevier B.V.",

}

Tabrizi, L, Chiniforoshan, H & McArdle, P 2015, 'A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities', Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, vol. 139, pp. 307-312. https://doi.org/10.1016/j.saa.2014.12.072

A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities. / Tabrizi, Leila; Chiniforoshan, Hossein; McArdle, Patrick.
In: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol. 139, 15.03.2015, p. 307-312.

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

TY - JOUR

T1 - A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands

T2 - Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities

AU - Tabrizi, Leila

AU - Chiniforoshan, Hossein

AU - McArdle, Patrick

PY - 2015/3/15

Y1 - 2015/3/15

N2 - A novel 1D coordination polymer {[Mn(μ1,5-dca)2(PZA)2](PZA)2}n, 1, has been synthesized and characterized by single crystal X-ray crystallography. The coordination mode of dicyanamide (dca) and pyrazinamide (PZA) ligands was inferred by IR spectroscopy. The compound 1 was evaluated for in vitro antimycobacterial and antitumor activities. It demonstrated better in vitro activity against Mycobacterium tuberculosis than pyrazinamide and its MIC value was determined. Complex 1 was also screened for its in vitro antitumor activity towards LM3 and LP07 murine cancer cell lines. In addition, the antibacterial activity of complex 1 has been tested against Gram(+) and Gram(-) bacteria and it has shown promising broad range anti-bacterial activity.

AB - A novel 1D coordination polymer {[Mn(μ1,5-dca)2(PZA)2](PZA)2}n, 1, has been synthesized and characterized by single crystal X-ray crystallography. The coordination mode of dicyanamide (dca) and pyrazinamide (PZA) ligands was inferred by IR spectroscopy. The compound 1 was evaluated for in vitro antimycobacterial and antitumor activities. It demonstrated better in vitro activity against Mycobacterium tuberculosis than pyrazinamide and its MIC value was determined. Complex 1 was also screened for its in vitro antitumor activity towards LM3 and LP07 murine cancer cell lines. In addition, the antibacterial activity of complex 1 has been tested against Gram(+) and Gram(-) bacteria and it has shown promising broad range anti-bacterial activity.

KW - Antibacterial activity

KW - Antitumor activity

KW - Dicyanamide

KW - Manganese(II)

KW - Pyrazinamide

UR - https://www.scopus.com/pages/publications/84920725992

U2 - 10.1016/j.saa.2014.12.072

DO - 10.1016/j.saa.2014.12.072

M3 - Article

SN - 1386-1425

VL - 139

SP - 307

EP - 312

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

ER -

Tabrizi L, Chiniforoshan H, McArdle P. A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2015 Mar 15;139:307-312. doi: 10.1016/j.saa.2014.12.072

A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: Synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities

Abstract

UN SDGs

Keywords

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